Counter-propagating wave interaction for contrast-enhanced ultrasound imaging
| Autor: | Johannes G. Bosch, G. L. ten Kate, A.F.W. van der Steen, Guillaume Renaud, N. de Jong, Vijay Shamdasani, Robert R. Entrekin |
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| Přispěvatelé: | Cardiology, Internal Medicine |
| Rok vydání: | 2012 |
| Předmět: |
Physics
Scanner Microbubbles Radiological and Ultrasound Technology business.industry Acoustics media_common.quotation_subject Contrast Media Pulse sequence Acoustic wave Imaging phantom Amplitude modulation Carotid Arteries Optics Nonlinear Dynamics Image Processing Computer-Assisted Contrast (vision) Radiology Nuclear Medicine and imaging Artifacts business Ultrasonography Contrast-enhanced ultrasound media_common |
| Zdroj: | Physics in Medicine and Biology, 57(21), L9-L18. IOP Publishing Ltd. |
| ISSN: | 0031-9155 |
| Popis: | Most techniques for contrast-enhanced ultrasound imaging require linear propagation to detect nonlinear scattering of contrast agent microbubbles. Waveform distortion due to nonlinear propagation impairs their ability to distinguish microbubbles from tissue. As a result, tissue can be misclassified as microbubbles, and contrast agent concentration can be overestimated; therefore, these artifacts can significantly impair the quality of medical diagnoses. Contrary to biological tissue, lipid-coated gas microbubbles used as a contrast agent allow the interaction of two acoustic waves propagating in opposite directions (counter-propagation). Based on that principle, we describe a strategy to detect microbubbles that is free from nonlinear propagation artifacts. In vitro images were acquired with an ultrasound scanner in a phantom of tissue-mimicking material with a cavity containing a contrast agent. Unlike the default mode of the scanner using amplitude modulation to detect microbubbles, the pulse sequence exploiting counter-propagating wave interaction creates no pseudoenhancement behind the cavity in the contrast image. |
| Databáze: | OpenAIRE |
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