Antibacterial effect of silver nanorings
| Autor: | Mª. Fe Menéndez, Fernando Vázquez, Carla Martín, Luis J. Andrés, David Rodríguez, Luis M. Quirós, Beatriz García, Sara González-Fernández, Víctor Lozano-Iturbe |
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| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
Silver Drug Compounding lcsh:QR1-502 Metal Nanoparticles Nanoparticle Microbial Sensitivity Tests 02 engineering and technology Antibacterial effect Silver nanowires Microbiology Silver nanoparticle lcsh:Microbiology 03 medical and health sciences Salmonella Drug Resistance Bacterial 030304 developmental biology Silver nanorings 0303 health sciences Microbial Viability Dose-Response Relationship Drug biology Planktonic bacteria Biofilm 021001 nanoscience & nanotechnology biology.organism_classification Silver nanospheres Anti-Bacterial Agents Nanostructures Biofilms Culture Media Conditioned Biophysics Antibacterials Antibacterial action Silver nanoparticles 0210 nano-technology Bacteria Research Article |
| Zdroj: | BMC Microbiology, Vol 20, Iss 1, Pp 1-14 (2020) Scopus RUO. Repositorio Institucional de la Universidad de Oviedo instname BMC Microbiology RUO: Repositorio Institucional de la Universidad de Oviedo Universidad de Oviedo (UNIOVI) |
| DOI: | 10.21203/rs.2.19184/v3 |
| Popis: | Background The emergence and expansion of antibiotic resistance makes it necessary to have alternative anti-infective agents, among which silver nanoparticles (AgNPs) display especially interesting properties. AgNPs carry out their antibacterial action through various molecular mechanisms, and the magnitude of the observed effect is dependent on multiple, not fully understood, aspects, particle shape being one of the most important. In this article, we conduct a study of the antibacterial effect of a recently described type of AgNP: silver nanorings (AgNRs), making comparisons with other alternative types of AgNP synthesized in parallel using the same methodology. Results When they act on planktonic forms, AgNRs produce a smaller effect on the viability of different bacteria than nanoparticles with other structures although their effect on growth is more intense over a longer period. When their action on biofilms is analyzed, AgNRs show a greater concentration-dependent effect. In both cases it was observed that the effect on inhibition depends on the microbial species, but not its Gram positive or negative nature. Growth patterns in silver-resistant Salmonella strains suggest that AgNRs work through different mechanisms to other AgNPs. The antibacterial effect is also produced to some extent by the conditioning of culture media or water by contact with AgNPs but, at least over short periods of time, this is not due to the release of Ag ions. Conclusions AgNRs constitute a new type of AgNP, whose antibacterial properties depend on their shape, and is capable of acting efficiently on both planktonic bacteria and biofilms. |
| Databáze: | OpenAIRE |
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