Theory of pH-stat titration
| Autor: | Elena Ficara, Paola Cortelezzi, Alberto Rozzi |
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| Rok vydání: | 2003 |
| Předmět: |
Validation study
Chromatography Inorganic chemistry Carbonates Titrimetry Bioengineering Carbon Dioxide Hydrogen-Ion Concentration Models Biological Applied Microbiology and Biotechnology Feedback Bicarbonates chemistry.chemical_compound Bioreactors Models Chemical chemistry Total inorganic carbon Carbon dioxide Bioreactor Computer Simulation Titration Nitrification Operational stability Biotechnology |
| Zdroj: | Biotechnology and Bioengineering. 82:28-37 |
| ISSN: | 1097-0290 0006-3592 |
| DOI: | 10.1002/bit.10541 |
| Popis: | Innovative techniques are being studied to assess the activity of bioreactors and to improve the performance and operational stability of biological processes. Among these techniques, the pH-stat titration is applicable to any bioreaction involving pH variations. Up to now, the main application of the pH-stat titration has been for nitrification monitoring. In this article, we present a theoretical model of pH-stat titration, which predicts the response to any reaction involving the production or consumption of protons, hydroxyl ions, or inorganic carbon chemical species (CO(2), HCO(3)(-), CO(3)(=)). This model is a useful tool to understand pH-stat titrations, to define their applicability and limits, and to select the best experimental conditions for specific applications. Tests have been performed to compare experimental pH-stat titration rates in the presence of carbon dioxide and HCO(3)(-) producing reactions to the values predicted by the model and a very satisfying correspondence was found. |
| Databáze: | OpenAIRE |
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