Daratumumab is safe and induces a rapid hematological response in light-chain amyloidosis with severe cardiac impairment
| Autor: | Corinne Haioun, Asma Beldi-Ferchiou, Amandine Ladaique, Jehan Dupuis, Louise Roulin, S. Oghina, Thibaud Damy, Diane Bodez, François Lemonnier, Alizee Maarek, Karim Belhadj, Fabien Le Bras, Romain Gounot, Elsa Poullot, Valérie Molinier-Frenkel |
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| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty Chemistry Amyloidosis Organ dysfunction Antibodies Monoclonal Daratumumab Hematological response Hematology Immunoglobulin light chain medicine.disease 03 medical and health sciences 0302 clinical medicine Oncology 030220 oncology & carcinogenesis Plasma cell disorder medicine Extracellular Humans medicine.symptom Deposition (chemistry) 030215 immunology |
| Zdroj: | Leukemia & Lymphoma. 62:979-983 |
| ISSN: | 1029-2403 1042-8194 |
| Popis: | Systemic light-chain (AL) amyloidosis is a plasma cell disorder characterized by extracellular deposition of monoclonal immunoglobulin light chains leading to organ dysfunction. Cardiac involvement... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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