Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm
| Autor: | Marcin Hartel, Monika Rudzińska, Michalina Malec, Magdalena Wójcik-Pędziwiatr, Natalia Grabska, Andrzej Szczudlik |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Cerebellopontine Angle Logistic regression White People Cohort Studies Risk Factors Internal medicine medicine Humans Hemifacial Spasm Risk factor Aged business.industry Small volume Cistern Middle Aged Neurovascular bundle medicine.disease Cerebellopontine angle Magnetic Resonance Imaging Surgery medicine.anatomical_structure Cranial Fossa Posterior Posterior cranial fossa Hypertension Cardiology Female Poland Neurology (clinical) business Hemifacial spasm |
| Popis: | Objectives: So far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients. Materials and methods: The study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans. Results: There were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p = 0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p = 0.047). In the subgroup of |
| Databáze: | OpenAIRE |
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