Fatal nosocomial hemorrhagic enterocolitis probably caused by adenovirus. Report of one case
| Autor: | Alberto Fica, Arturo Escalona, Diana Aceituno, María Ignacia Villarroel, Pabla Cataldo |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Diarrhea medicine.medical_specialty medicine.drug_class Adenoviridae Infections medicine.medical_treatment Colonoscopy Gastroenterology Racecadotril Adenoviridae Immunocompromised Host 03 medical and health sciences Fatal Outcome 0302 clinical medicine Adrenal Cortex Hormones Internal medicine medicine Humans 030212 general & internal medicine Mechanical ventilation Cross Infection medicine.diagnostic_test Enterocolitis business.industry Clinical course General Medicine Acute Kidney Injury Hemorrhagic enterocolitis Corticosteroid Female Hemodialysis medicine.symptom Gastrointestinal Hemorrhage business medicine.drug |
| Zdroj: | Revista médica de Chile v.147 n.2 2019 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| DOI: | 10.4067/s0034-98872019000200256 |
| Popis: | Adenovirus (ADV) is a recognized cause of severe disease among immunocompromised patients. We report a previously healthy 39-year-old female, admitted with influenza pneumonia and evolving with lung hemorrhage and acute renal failure requiring mechanical ventilation and hemodialysis. She received high corticosteroid doses due to an initial suspicion of alveolar hemorrhage. Lymphopenia already present before steroid use (567/μL), was maintained during the whole hospital stay (mean 782/μL). From the second week of admission she presented a high-volume diarrhea (mean 2.5 L/day) associated to intermittent bloody stools. An ulcerative enterocolitis was confirmed by CT images and colonoscopy. ADV was detected in a colonic tissue sample by real time PCR but not by a commercial filmarray test. Cidofovir-probenecid and racecadotril therapy were indicated without changing the clinical course of diarrhea and the patient finally died. |
| Databáze: | OpenAIRE |
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