Identification by genome mining of a type I polyketide gene cluster from Streptomyces argillaceus involved in the biosynthesis of pyridine and piperidine alkaloids argimycins P
| Autor: | Brian Molloy, Alfredo F. Braña, Carlos Olano, José A. Salas, Jesus Cortes, Suhui Ye, Francisco Morís, Carmen Méndez, Daniel Zabala |
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| Rok vydání: | 2017 |
| Předmět: |
pyridine
0301 basic medicine Microbiology (medical) biology growth 030106 microbiology Hypothetical protein Repressor piperidine alkaloid biology.organism_classification Microbiology Streptomyces thioester reductase 03 medical and health sciences Polyketide 030104 developmental biology Thioesterase Biochemistry Flavin reductase Gene cluster Gene cryptic type I polyketide synthase |
| Zdroj: | Scopus RUO. Repositorio Institucional de la Universidad de Oviedo instname |
| Popis: | Ministry of Economy This work was supported by grants to CM from the Spanish Ministry of Economy and Competitiveness, MINECO (Grants BIO2011-25398, BIO2014-56752-R and PIM2010EEI-00752) and “Apoyo a grupos de excelencia,” Principado de Asturias-FEDER (FC-15-GRUPIN14-014). EntreChem SL acknowledges funding to the ERA-IB program and MINECO (PIM2010EEI-00752). SY and DZ were recipient of predoctoral fellowships from MINECO. We thank Fundación Bancaria Cajastur for financial support to CO, and we also thank Dr. Fernando Reyes from Fundación Medina, and Dr. Javier González-Sabín and Dr. Nicolás Ríos-Lombardía from Entrechem S.L. for technical support in structural elucidation compounds. |
| Databáze: | OpenAIRE |
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