Evaluation of Adenovirus-36 (Ad-36) antibody seropositivity and adipokine levels in obese children
| Autor: | Olcay Evliyaoğlu, Bahar Ozcabi, Nergiz Imamova, Sevgi Ergin, Suat Saribas, Utku Y. Cizmecigil, Harika Oyku Dinc, Huseyin Yilmaz, Nuri Turan, Penbe Cagatay, Asiye Karakullukcu, Kevser Atalik, Zeynep Taner, Eda Altan, Pelin Yuksel, Bekir Kocazeybek, Serhat Sirekbasan |
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| Přispěvatelé: | DİNÇ, HARİKA ÖYKÜ, YÜKSEL MAYDA, PELİN |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Leptin Male medicine.medical_specialty Adolescent Turkey Adipokine 030209 endocrinology & metabolism Enzyme-Linked Immunosorbent Assay Antibodies Viral Microbiology Body Mass Index Adenovirus Infections Human 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Adipokines Neutralization Tests Risk Factors Internal medicine medicine Prevalence Humans Obesity Child Triglycerides biology Adiponectin Cholesterol business.industry Interleukin-6 Adenoviruses Human Case-control study medicine.disease Lipids 030104 developmental biology Infectious Diseases Endocrinology chemistry Case-Control Studies biology.protein Female Antibody business Body mass index |
| Zdroj: | Microbial pathogenesis. 108 |
| ISSN: | 1096-1208 |
| Popis: | Adenovirus 36 (Ad-36) has recently been suggested as a possible contributor to the current obesity epidemic. The aim of this study was to investigate the prevalence of Ad-36 antibodies in obese children, as well as investigate the role of serum leptin and lipid levels in Ad-36-obesity. Seventy-one obese children and 62 non-obese children were included as the patient group (PG), including the healthy control group (HCG), respectively. Simultaneously, Ad-36 antibodies and adipokine levels were assessed with serum neutralization assays (SNA) and ELISA. Ad-36 antibody was detected in 9 patients (12.7%) and 1 patient (1.6%) in both the PG and HCG, respectively, while a significant difference was detected between groups (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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