Cardiovascular Side Effects of Anthracyclines and HER2 Inhibitors among Patients with Breast Cancer: A Multidisciplinary Stepwise Approach for Prevention, Early Detection, and Treatment

Autor: Ciro Mauro, Valentina Capone, Rosangela Cocchia, Filippo Cademartiri, Ferdinando Riccardi, Michele Arcopinto, Maie Alshahid, Kashif Anwar, Mariano Carafa, Andreina Carbone, Rossana Castaldo, Salvatore Chianese, Giulia Crisci, Roberta D’Assante, Mariarosaria De Luca, Monica Franzese, Domenico Galzerano, Vincenzo Maffei, Alberto M. Marra, Valeria Valente, Federica Giardino, Alfredo Mazza, Brigida Ranieri, Anna D’Agostino, Salvatore Rega, Luigia Romano, Sarah Scagliarini, Chiara Sepe, Olga Vriz, Raffaele Izzo, Antonio Cittadini, Eduardo Bossone, Andrea Salzano
Přispěvatelé: Mauro, Ciro, Capone, Valentina, Cocchia, Rosangela, Cademartiri, Filippo, Riccardi, Ferdinando, Arcopinto, Michele, Alshahid, Maie, Anwar, Kashif, Carafa, Mariano, Carbone, Andreina, Castaldo, Rossana, Chianese, Salvatore, Crisci, Giulia, D'Assante, Roberta, De Luca, Mariarosaria, Franzese, Monica, Galzerano, Domenico, Maffei, Vincenzo, Marra, Alberto M, Valente, Valeria, Giardino, Federica, Mazza, Alfredo, Ranieri, Brigida, D'Agostino, Anna, Rega, Salvatore, Romano, Luigia, Scagliarini, Sarah, Sepe, Chiara, Vriz, Olga, Izzo, Raffaele, Cittadini, Antonio, Bossone, Eduardo, Salzano, Andrea
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Popis: Cardiovascular (CV) diseases (CVD) are a major cause of long-term morbidity and mortality affecting life expectancy amongst cancer survivors. In recent years, because of the possibility of early diagnosis and the increased efficacy of neo-adjuvant and adjuvant systemic treatments (targeting specific molecular pathways), the high percentage of survival from breast cancer led CVD to become the first cause of death among survivors. Therefore, it is mandatory to adopt cardioprotective strategies to minimize CV side effects and CVD in general in breast cancer patients. Cancer therapeutics-related cardiac dysfunction (CTRCD) is a common group of side effects of chemotherapeutics widely employed in breast cancer (e.g., anthracycline and human epidermal growth factor receptor 2 inhibitors). The aim of the present manuscript is to propose a pragmatic multidisciplinary stepwise approach for prevention, early detection, and treatment of cardiotoxicity in patients with breast cancer.
Databáze: OpenAIRE