COVID-19 pandemic and stent thrombosis in a post percutaneous coronary intervention patient-a case report highlighting the selection of P2Y12 inhibitor
| Autor: | Atul Kaushik, Jai Bharat Sharma, Rahul Choudhary |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Acute coronary syndrome
medicine.medical_specialty business.industry medicine.medical_treatment ST elevation Percutaneous coronary intervention Case Report 030204 cardiovascular system & hematology medicine.disease Clopidogrel 03 medical and health sciences 0302 clinical medicine Drug-eluting stent Internal medicine Right coronary artery medicine.artery Conventional PCI medicine Cardiology cardiovascular diseases 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Ticagrelor medicine.drug |
| Zdroj: | Cardiovasc Diagn Ther |
| ISSN: | 2223-3660 2223-3652 |
| DOI: | 10.21037/cdt-20-485 |
| Popis: | The current pandemic of novel coronavirus disease 2019 (COVID‐19) has posed a great threat to people’s health worldwide, with specific implications on patients with underlying heart diseases. During this challenging period, nearly all major societies have recommended for conservative approach, even for patients with relatively stable acute cardiovascular diseases. Selection of specific antiplatelet therapy in an uncomplicated post percutaneous coronary intervention (PCI) patient can, at times, be crucial issue in such strained circumstances. We report a case of 64-year-old male, who was taken for urgent coronary angiogram (CAG) in view of non ST elevation acute coronary syndrome. Successful PCI with implantation of drug eluting stent was done for right coronary artery (RCA) and left anterior descending (LAD) artery lesions. On day 5th post-PCI, he developed acute inferior wall STEMI due to subacute stent thrombosis (ST), and despite all efforts, patient could not be saved as he didn’t receive timely intervention. Increased travel time to emergency department due to lockdown because of COVID-19 and along with extra time required for donning of personal protection equipment (PPE) and other COVID-19 related safety measures prolonged the ischemic time. Potent P2Y12 inhibitor based dual antiplatelet therapy might have prevented this subacute ST, and thus mortality, as the patient was discharged on clopidogrel after PCI. While selecting specific P2Y12 inhibitor in a post PCI patient, apart from clinical condition of patient and complexity of procedure, we should also consider current COVID-19 pandemic. Current circumstances may favour ticagrelor over other P2Y12 inhibitors in view of its potent, rapid, and reversible antiplatelet action along with its optimistic effect in pneumonia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|