Effect of Intensive Blood-Pressure Treatment on Patient-Reported Outcomes
| Autor: | Thomas Ramsey, Tanya R. Gure, Lewis E. Kazis, Daniel E. Weiner, James R. Powell, Dan R. Berlowitz, Peter M. Fitzpatrick, Debra L. Simmons, Molly B. Conroy, Donald E. Morisky, Jill C. Newman, Suzanne Oparil, Joni K. Snyder, Paul L. Kimmel, Linda P. Bolin, Capri G. Foy, Christine M. Olney, Kent Kirchner, Mark A. Supiano, Jeff Whittle, Nicholas M. Pajewski |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Depression scale Standard treatment General Medicine 030204 cardiovascular system & hematology medicine.disease Article law.invention Patient Health Questionnaire 03 medical and health sciences 0302 clinical medicine Blood pressure Patient satisfaction Pharmacotherapy Randomized controlled trial law Diabetes mellitus Internal medicine medicine Physical therapy 030212 general & internal medicine business |
| Zdroj: | New England Journal of Medicine. 377:733-744 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejmoa1611179 |
| Popis: | BackgroundThe previously published results of the Systolic Blood Pressure Intervention Trial showed that among participants with hypertension and an increased cardiovascular risk, but without diabetes, the rates of cardiovascular events were lower among those who were assigned to a target systolic blood pressure of less than 120 mm Hg (intensive treatment) than among those who were assigned to a target of less than 140 mm Hg (standard treatment). Whether such intensive treatment affected patient-reported outcomes was uncertain; those results from the trial are reported here. MethodsWe randomly assigned 9361 participants with hypertension to a systolic blood-pressure target of less than 120 mm Hg or a target of less than 140 mm Hg. Patient-reported outcome measures included the scores on the Physical Component Summary (PCS) and Mental Component Summary (MCS) of the Veterans RAND 12-Item Health Survey, the Patient Health Questionnaire 9-item depression scale (PHQ-9), patient-reported satisfaction with their... |
| Databáze: | OpenAIRE |
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