Apoptosis, cell proliferation and expression of Bcl-2 and Bax in gastric carcinomas: immunohistochemical and clinicopathological study
| Autor: | Y Koshida, I Okayasu, M Saegusa |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty Programmed cell death Mitotic index Apoptosis Adenocarcinoma Biology Bcl-2-associated X protein Stomach Neoplasms Proto-Oncogene Proteins Mitotic Index medicine Carcinoma Humans Neoplasm Invasiveness Lymph node Neoplasm Staging bcl-2-Associated X Protein Prognosis medicine.disease Immunohistochemistry medicine.anatomical_structure Proto-Oncogene Proteins c-bcl-2 Oncology Lymphatic Metastasis Cancer research biology.protein Carcinoma Signet Ring Cell Cell Division Research Article |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/bjc.1997.60 |
| Popis: | To clarify the relation between bcl-2 and bax protein (Bcl-2 and Bax) expression with regard to apoptosis and cell proliferation, 82 gastric carcinomas were immunohistochemically investigated. The significance of apoptosis for biological behaviour of the tumours was also examined. The apoptotic indices (AIs) were significantly lower in early-stage than in advanced-stage lesions (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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