Antibacterial efficacy of silver diamine fluoride as a root canal irrigant
| Autor: | Albandary M. Al‐Owid, Ebtissam M. Al-Madi, Manar Al-Jamie, Amal A. Almohaimede, Noura. M. Al-Owaid |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Enterococcus faecalis irrigation chemistry.chemical_compound medicine Dentin Humans Fluorides Topical Silver diamine fluoride Food science General Dentistry Saline Gram-Positive Bacterial Infections Root Canal Irrigants biology Chemistry Chlorhexidine chlorhexidine Biofilm Silver Compounds Original Articles Endodontics biology.organism_classification Quaternary Ammonium Compounds lcsh:RK1-715 endodontics medicine.anatomical_structure Biofilms Sodium hypochlorite lcsh:Dentistry antimicrobial Original Article nanoparticles Disinfectants medicine.drug |
| Zdroj: | Clinical and Experimental Dental Research, Vol 5, Iss 5, Pp 551-556 (2019) Clinical and Experimental Dental Research |
| ISSN: | 2057-4347 |
| Popis: | Objectives Conventional disinfectants and medicaments have not been able to achieve and maintain sterilization of root canals. The purpose of the study was to evaluate the antibacterial efficacy of 3.8% silver diamine fluoride (SDF) in comparison with 2% chlorhexidine (CHX) against Enterococcus faecalis biofilm. Materials and methods Extracted human teeth were used to make 70 dentin discs that were then inoculated with E. faecalis to generate a 3‐week‐old biofilm model. The discs were subjected to treatment with 3.8% SDF, 2% CHX, sodium hypochlorite (NaOCl), or saline for 10 min. After exposure, the dentin discs were examined with a confocal laser scanning microscope to verify the percentage of live versus dead cells within the biofilm. Univariate one‐way analysis of variance and Tukey‐honestly significant difference post hoc analysis (p < .05) were performed to detect significant differences. Results and conclusion The NaOCl group showed the greatest percentage of dead cells (62.26%) among all groups (p < .05). The SDF group showed a significantly higher percentage of dead cells (57.39%) than the 2% CHX and saline groups (p < .05). SDF possessed higher antimicrobial activity than 2% CHX against E. faecalis biofilms. |
| Databáze: | OpenAIRE |
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