Risk factors for lung cancer worldwide
Autor: | Malhotra, J., MALVEZZI, MONICA, NEGRI, ELISA, La Vecchia, C., Boffetta, P., NEGRI, EVA VANNA LORENZA |
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Přispěvatelé: | Malhotra, J., Malvezzi, M., Negri, E., La Vecchia, C., Boffetta, P. |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Pulmonary and Respiratory Medicine Male Pathology medicine.medical_specialty Lung Neoplasms Alcohol Drinking Disease medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Risk Factors Environmental health Occupational Exposure Epidemiology of cancer Tobacco medicine Genetic predisposition Humans Genetic Predisposition to Disease Lung cancer Inflammation Lung Polymorphism Genetic business.industry Incidence Smoking respiratory system Descriptive epidemiology medicine.disease respiratory tract diseases Diet 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Etiology Female Carcinogenesis business |
Zdroj: | The European respiratory journal. 48(3) |
ISSN: | 1399-3003 |
Popis: | Lung cancer is the most frequent malignant neoplasm in most countries, and the main cancer-related cause of mortality worldwide in both sexes combined.The geographic and temporal patterns of lung cancer incidence, as well as lung cancer mortality, on a population level are chiefly determined by tobacco consumption, the main aetiological factor in lung carcinogenesis.Other factors such as genetic susceptibility, poor diet, occupational exposures and air pollution may act independently or in concert with tobacco smoking in shaping the descriptive epidemiology of lung cancer. Moreover, novel approaches in the classification of lung cancer based on molecular techniques have started to bring new insights to its aetiology, in particular among nonsmokers. Despite the success in delineation of tobacco smoking as the major risk factor for lung cancer, this highly preventable disease remains among the most common and most lethal cancers globally.Future preventive efforts and research need to focus on non-cigarette tobacco smoking products, as well as better understanding of risk factors underlying lung carcinogenesis in never-smokers. |
Databáze: | OpenAIRE |
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