Gastroesophageal reflux in young children treated for esophageal atresia: evaluation with pH-multichannel intraluminal impedance
| Autor: | Anna Maria Caruso, Pieralba Catalano, Maria Rita Di Pace, Enrico De Grazia, Alessandra Casuccio |
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| Přispěvatelé: | Catalano, P, Di Pace, MR, Caruso, AM, Casuccio, A, De Grazia, E |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Esophageal pH Monitoring Tracheoesophageal fistula Settore MED/42 - Igiene Generale E Applicata Gastroenterology Gastric Acid Esophagus Postoperative Complications Bolus (medicine) Internal medicine medicine Humans Gastrointestinal Transit Esophageal Atresia esophageal atresia esophageal dismotility gastroesophageal reflux disease multichannel intraluminal impedance ph-metry Esophageal disease business.industry fungi Significant difference Settore MED/20 - Chirurgia Pediatrica E Infantile Reflux Infant Hydrogen-Ion Concentration medicine.disease medicine.anatomical_structure El Niño Case-Control Studies Child Preschool Atresia Pediatrics Perinatology and Child Health Gastroesophageal Reflux business Tracheoesophageal Fistula |
| Popis: | Objectives: Gastroesophageal reflux (GER) and dismotility occur frequently after repair of esophageal atresia (EA). GER-associated complications can manifest either early or later; then precocious diagnosis and treatment are essential. The aim of the study was to evaluate characteristics of GER and esophageal clearance in children treated for EA with distal tracheoesophageal fistula, using pH-multichannel intraluminal impedance (pH-MII). Patients and Methods: Twenty-two children (ages 3‐40 months) treated for EA at birth, and 20 normal children of similar age with suspected GER disease were included in the study. Impedance parameters were analyzed according to age and symptoms. Results: Reflux events were mainly nonacidic. About bolus exposure index, mean acid clearing time (MACT), and mean bolus clearing time (MBCT), a significant difference was found between 2 groups: the median MACT and MBCT were longer, with values of 281 and 39 seconds, respectively, in the EA group and 110 and 15 seconds in the control group (P |
| Databáze: | OpenAIRE |
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