Cerebral 1H MR spectroscopy revealing white matter NAA decreases in glutaric aciduria type I

Autor:	Linda C. Meiners, van FrancJan Spronsen, Gerrit Smit, Paul E. Sijens, Matthijs Oudkerk
Přispěvatelé:	Faculteit Medische Wetenschappen/UMCG, Center for Liver, Digestive and Metabolic Diseases (CLDM)
Rok vydání:	2006
Předmět:	Male In vivo magnetic resonance spectroscopy 1h nmr spectroscopy Endocrinology Diabetes and Metabolism Biochemistry White matter Endocrinology Nuclear magnetic resonance Glutamates Image Processing Computer-Assisted Genetics medicine Humans ACUTE STRIATAL NECROSIS Child Amino Acid Metabolism Inborn Errors Molecular Biology Aspartic Acid Glutaryl-CoA Dehydrogenase Chemistry Glutaric aciduria Glutamate receptor Brain Magnetic Resonance Imaging magnetic resonance spectroscopy BRAIN-TUMOR medicine.anatomical_structure brain metabolism Child Preschool Lactates Female glutaric aciduria type I Inositol
Zdroj:	Molecular Genetics and Metabolism, 88(3), 285-289. ACADEMIC PRESS INC ELSEVIER SCIENCE
ISSN:	1096-7192
Popis:	MR spectroscopy in two patients with glutaric aciduria type I revealed reductions in the white matter N-acetylaspartate signal, in the more severe case accompanied by a loss of glutamate and the appearance of lactate signals. (c) 2006 Elsevier Inc. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc418574fe3b5a9a272cdb67f2d15f1 https://doi.org/10.1016/j.ymgme.2006.01.001 Zobrazit plný text záznamu Full Text from ScienceDirect