Eosinophilic Leukaemia and Systemic Mycobacterium marinum Infection in an African Pygmy Hedgehog (Atelerix albiventris)
| Autor: | Kiyokazu Ozaki, Shin-ichi Nakamura, Masaru Yasuda, Takamitsu Tsukahara |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Pathology medicine.medical_specialty 040301 veterinary sciences Mycobacterium Infections Nontuberculous Spleen 030308 mycology & parasitology Pathology and Forensic Medicine 0403 veterinary science 03 medical and health sciences Lethargy RNA Ribosomal 16S Hypereosinophilic Syndrome medicine Animals Hedgehog Lymph node Mycobacterium marinum 0303 health sciences Kidney Lung General Veterinary biology business.industry Atelerix albiventris 04 agricultural and veterinary sciences biology.organism_classification medicine.anatomical_structure Hedgehogs business |
| Zdroj: | Journal of Comparative Pathology. 181:33-37 |
| ISSN: | 0021-9975 |
| DOI: | 10.1016/j.jcpa.2020.09.013 |
| Popis: | Summary A two-year-old male African pygmy hedgehog (Atelerix albiventris) presented with lethargy and anorexia. Ultrasonographic and radiographic examinations revealed splenomegaly and pneumonia, respectively. Prominent leucocytosis, consisting mainly of large atypical eosinophils, was observed in a peripheral blood smear. Necropsy revealed a black scab on the left hindlimb, which was swollen, an enlarged left inguinal lymph node, firm oedematous lungs, splenomegaly and multiple nodules in the lung, spleen and liver. Histopathologically, infiltration of numerous eosinophils was seen in lung, spleen, liver, kidney, lymph node and adrenal medulla tissues. Necrotizing granulomatous lesions, with intralesional acid-fast bacilli, were found in the lung, spleen, liver, left inguinal lymph node and left hindlimb. Mycobacterium marinum was identified by broad-range polymerase chain reaction targeting of the bacterial 16S rRNA gene. To the best of our knowledge, this is only the second reported case of systemic M. marinum infection in any mammalian species. |
| Databáze: | OpenAIRE |
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