Hypervascular hepatocellular carcinomas: detection with gadoxetate disodium-enhanced MR imaging and multiphasic multidetector CT
| Autor: | Seishi Kumano, Mitsuaki Tatsumi, Takamichi Murakami, Tonsok Kim, Masahiro Okada, Masatoshi Hori, Hiromitsu Onishi, Yasuharu Imai, Atsushi Nakamoto, Takahiro Tsuboyama, Manabu Takamura, Noriyuki Tomiyama, Kenichi Wakasa, Hiroaki Nagano, Yasuhiro Nakaya |
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| Rok vydání: | 2011 |
| Předmět: |
Gadolinium DTPA
medicine.medical_specialty Carcinoma Hepatocellular Contrast Media Sensitivity and Specificity Gadoxetate Disodium Liver disease Carcinoma Humans Medicine Radiology Nuclear Medicine and imaging Aged Retrospective Studies Neuroradiology Aged 80 and over Observer Variation Neovascularization Pathologic medicine.diagnostic_test business.industry Liver Neoplasms Ultrasound Reproducibility of Results Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Hepatocellular carcinoma Female Tomography Radiology Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | European Radiology. 22:845-854 |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-011-2316-y |
| Popis: | To retrospectively compare the accuracy of detection of hypervascular hepatocellular carcinoma (HCC) by multiphasic multidetector CT and by gadoxetate disodium-enhanced MR imaging. After ethical approval, we analysed a total of 73 hypervascular HCC lesions from 31 patients suspected of having HCC, who underwent both gadoxetate disodium-enhanced MR imaging and multiphasic multidetector CT. Five blinded observers independently reviewed CT images, as well as dynamic MR images alone and combined with hepatobiliary phase MR images. Diagnostic accuracy (Az values), sensitivities and positive predictive values were compared by using the Scheffe post hoc test. The mean Az value for dynamic and hepatobiliary phase MR combined (0.81) or dynamic MR images alone (0.78) was significantly higher than that for CT images (0.67, P |
| Databáze: | OpenAIRE |
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