Research activity and capability in the European reference network MetabERN

Autor: Heard, J. -M., Bellettato, C, Van, Lingen, Scarpa, M, Debray, F. -G., Nassogne, M. -C., Van, Coster, Meirleir, De, Eyskens, L., Morava, F., Baric, E., Kozich, I., Lund, V., Germain, A. M., Belmatoug, D., Guffon, N., Labrune, N., Gouya, P., Lonlay, De, Schiff, P., Dobbelaere, M., Chabrol, D., Das, B., Spiekerkoetter, A. M., Rutsch, U., Ploeckinger, F., Mohnike, U., Hahn, K., Kölker, A., Ullrich, S., Balogh, K., Bembi, I., Donati, B., Gasperini, M. A., Parenti, S., Salviati, G., Vici, A., C. -D., Rocco, Di, Cefalo, M., Burlina, G., Ceccarini, G., Federico, A., Van Der Ploeg, Rubio-Gozalbo, A., M. -E., Van, Spronsen, Visser, F., Bosch, G., Tangeraas, A., Sanderberg, T., Kieć-Wilk, S., Gaspar, B., A. -M. S. M., Martins, E., Silva, E. -M. F. R., De Abreu Freire Diogo Matos, L. -M., Azevedo, O., Tansek, M. -Z., Couce-Pico, M. -L., Cazorla, A. G., Azuara, L. A. -E., Del, Toro-Riera, Lajic, M., Darin, S., Deegan, N., Vijaym, P., Chronopoulou, S., Jones, E., Chakrapani, S., Hiwot, A.
Přispěvatelé: Pediatrics, MetabERN Collaboration Grp, RS: GROW - R4 - Reproductive and Perinatal Medicine, Kindergeneeskunde, MUMC+: MA Medische Staf Kindergeneeskunde (9), VU University medical center, Amsterdam Reproduction & Development (AR&D), Paediatric Metabolic Diseases, AGEM - Inborn errors of metabolism
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Interdisciplinary Research/methods
0301 basic medicine
media_common.quotation_subject
Interdisciplinary Research
Medical research activity
lcsh:Medicine
030105 genetics & heredity
Research Support
BIOBANKS
03 medical and health sciences
Social support
Hereditary metabolic diseases
REGISTRIES
0302 clinical medicine
Quality of life (healthcare)
Excellence
Surveys and Questionnaires
Medicine and Health Sciences
Journal Article
Humans
media_common.cataloged_instance
Pharmacology (medical)
European union
Non-U.S. Gov't
Empowerment
Genetics (clinical)
media_common
European reference Centres
Multidisciplinary research
Medical education
Descriptive statistics
Research Support
Non-U.S. Gov't
Research
lcsh:R
General Medicine
Biobank
Europe
Respondent
Quality of Life
Human medicine
Business
RARE DISEASES
030217 neurology & neurosurgery
Zdroj: Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-9 (2019)
Orphanet Journal of Rare Diseases, 14:119. BioMed Central Ltd.
Heard, J-M, Bellettato, C, van Lingen, C, Scarpa, M, Debray, F-G, Nassogne, M-C C, van Coster, R, de Meirleir, L, Eyskens, F, Morava, E, Baric, I, Kozich, V, Lund, A M, Germain, D, Belmatoug, N, Guffon, N, Labrune, P, Gouya, L, de Lonlay, P, Schiff, M, Dobbelaere, D, Chabrol, B, Das, A M, Spiekerkoetter, U, Rutsch, F, Ploeckinger, U, Mohnike, K, Hahn, A, Kölker, S, Ullrich, K, Balogh, I, Bembi, B, Donati, M A, Gasperini, S, Parenti, G, Salviati, A, Vici, C-D, di Rocco, M, Cefalo, G, Burlina, A, Ceccarini, G, Federico, A, van der Ploeg, A, Rubio-Gozalbo, M-E, van Spronsen, F, Visser, G, Bosch, A, Tangeraas, T, Sanderberg, S, Kieć-Wilk, B, Gaspar, A-M S M, Martins, E, Silva, E-M F R, de Abreu Freire Diogo Matos, L-M, Azevedo, O, Tansek, M-Z, Couce-Pico, M-L, Cazorla, A G, Azuara, L A-E, del Toro-Riera, M, Lajic, S, Darin, N, Deegan, P, Vijaym, S, Chronopoulou, E, Jones, S, Chakrapani, A & Hiwot, T 2019, ' Research activity and capability in the European reference network MetabERN ', Orphanet Journal of Rare Diseases, vol. 14, no. 1, 119 . https://doi.org/10.1186/s13023-019-1091-8
Orphanet Journal of Rare Diseases
Orphanet journal of rare diseases
Orphanet Journal of Rare Diseases, 14:119. BioMed Central Ltd
ORPHANET JOURNAL OF RARE DISEASES
Orphanet Journal of Rare Diseases, 14(1):119. BioMed Central
Orphanet Journal of Rare Diseases, 14(1). BioMed Central
Orphanet journal of rare diseases, 14(1):119. BioMed Central
ISSN: 1750-1172
Popis: Background MetabERN is one of the 24 European Reference Networks created according to the European Union directive 2011/24/EU on patient’s rights in cross border healthcare. MetabERN associates 69 centres in 18 countries, which provide care for patients with Hereditary Metabolic Diseases, and have the mission to reinforce research and provide training for health professionals in this field. MetabERN performed a survey in December 2017 with the aim to produce an overview documenting research activities and potentials within the network. As the centres are multidisciplinary, separated questionnaires were sent to the clinical, university and laboratory teams. Answers were received from 52 out of the 69 centres of the network, covering 16 countries. A descriptive analysis of the information collected is presented. Results The answers indicate a marked interest of the respondents for research, who expressed high motivation and commitment, and estimated that the conditions to do research in their institution were mostly satisfactory. They are active in research, which according to several indicators, is competitive and satisfies standards of excellence, as well as the education programs offered in the respondent’s universities. Research in the centres is primarily performed in genetics, pathophysiology, and epidemiology, and focuses on issues related to diagnosis. Few respondents declared having activity in human and social sciences, including research on patient’s quality of life, patient’s awareness, or methods for social support. Infrastructures offering services for medical research were rarely known and used by respondents, including national and international biobanking platforms. In contrast, respondents often participate to patient registries, even beyond their specific field of interest. Conclusions Taken as a whole, these results provide an encouraging picture of the research capacities and activities in the MetabERN network, which, with respect to the number and representativeness of the investigated centres, gives a comprehensive picture of research on Hereditary Metabolic Diseases in Europe, as well as the priorities for future actions. Marginal activity in human and social sciences points out the limited multidisciplinary constitution of the responding teams with possible consequences on their current capability to participate to patient’s empowerment programs and efficiently collaborate with patient’s advocacy groups. Electronic supplementary material The online version of this article (10.1186/s13023-019-1091-8) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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