The Possible Role of Helicobacter pylori Infection in Non-alcoholic Fatty Liver Disease
| Autor: | Ying Huang, Cong He, Dandan Cheng, Nonghua Lu, Hong-hui Ai |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Pathology medicine.medical_specialty Mini Review lcsh:QR1-502 Chronic gastritis Disease Gut flora Gastroenterology digestive system Microbiology lcsh:Microbiology 03 medical and health sciences 0302 clinical medicine Internal medicine NAFLD insulin resistance medicine biology gut microbiota Stomach Fatty liver Cancer nutritional and metabolic diseases Helicobacter pylori biology.organism_classification medicine.disease bacterial infections and mycoses digestive system diseases lipid profile 030104 developmental biology medicine.anatomical_structure Etiology 030211 gastroenterology & hepatology H. pylori |
| Zdroj: | Frontiers in Microbiology Frontiers in Microbiology, Vol 8 (2017) |
| ISSN: | 1664-302X |
| Popis: | Helicobacter pylori (H. pylori) which colonizes the stomach can cause a wide array of gastric disorders, including chronic gastritis, peptic ulcer, and gastric cancer. Recently, accumulating evidence has implicated H. pylori infection in extragastrointestinal diseases such as cardiovascular diseases, neurological disorders, and metabolic diseases. At the same time, many scholars have noted the relationship between H. pylori infection and non-alcoholic fatty liver disease (NAFLD). Despite the positive association between H. pylori and NAFLD reported in some researches, there are opposite perspectives denying their relationship. Due to high prevalence, unclear etiology and difficult treatment of NAFLD, confirming the pathogenicity of H. pylori infection in NAFLD will undoubtedly provide insights for novel treatment strategies for NAFLD. This paper will review the relationship between H. pylori infection and NAFLD and the possible pathogenic mechanisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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