A Neurostimulation-Triggered Trigeminal Neuralgia-like Pain

Autor:	Gabriel Torrealba-Acosta, Haroon Butt, Rebecca Willaert, Alica M. Goldman, Everton A. Edmondson, Ashwin Viswanathan
Rok vydání:	2021
Předmět:	Valproic Acid Pediatrics medicine.medical_specialty Lacosamide business.industry Case Zonisamide Lamotrigine medicine.disease Epilepsy medicine Neurology (clinical) Levetiracetam Headaches medicine.symptom business Oxcarbazepine medicine.drug
Zdroj:	Neurol Clin Pract
ISSN:	2163-0933 2163-0402
DOI:	10.1212/cpj.0000000000001050
Popis:	The patient, a 21-year-old right-handed female had a complex history of a treatment resistant genetic epilepsy with febrile seizures plus syndrome (GEFS+), chronic migraine headaches, major depressive disorder (MDD), and anxiety. The epilepsy, paternally inherited and shared with an older sister, was resistant to treatment with phenobarbital, oxcarbazepine, valproic acid, zonisamide, and levetiracetam. The best, albeit incomplete seizure control was achieved with a combination therapy that included lamotrigine, lacosamide and topiramate. The treatment resistant character of the patient’s epilepsy prompted implantation of a VNS, model Aspire SR106. Gradual stimulation adjustment from a current output of 0.375 mA to 0.625 mA resulted in a reported full seizure control with only one breakthrough focal to bilateral tonic-clonic seizure triggered by a school-related stress and sleep deprivation in a 12-month period. The patient also experienced an improvement in mood and headaches.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb1ad4c54956e9416e8bb1f9625bdc1 https://doi.org/10.1212/cpj.0000000000001050 Zobrazit plný text záznamu