Thymus-dependent (T) lymphocyte deficiency in progressive systemic sclerosis
| Autor: | Janis Dodd, Shirley Holt, N.R. Rowell, P. Hughes |
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| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Erythrocytes T-Lymphocytes Dermatology Disease T-lymphocyte deficiency Scleroderma Pathogenesis Leukocyte Count Lymphopenia medicine Humans Immune adherence reaction Scleroderma Systemic Extensive Disease business.industry Progressive systemic sclerosis Middle Aged medicine.disease Immune Adherence Reaction stomatognathic diseases Immunological Factors Immunology Female business |
| Zdroj: | British Journal of Dermatology. 95:469-473 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1976.tb00855.x |
| Popis: | Circulating thymus-dependent (T) lymphocytes were estimated in twenty-seven patients with progressive systemic sclerosis (PSS) and in forty-five normal controls using the property of T lymphocytes to form rosettes with sheep red blood cells. The patients with PSS were found to have a reduction of T lymphocytes which correlated with the extent of visceral involvement by the disease, those with the lowest counts having the most extensive disease. These findings support the suggestion that immunological factors may be involved in the pathogenesis of PSS. |
| Databáze: | OpenAIRE |
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