Genetic Variation of Venezuelan Equine Encephalitis Virus Strains of the ID Variety in Colombia
| Autor: | R. W. Dickerman, D. W. Trent, R. Rico-Hesse, John T. Roehrig |
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| Rok vydání: | 1988 |
| Předmět: |
Genes
Viral Colombia Biology medicine.disease_cause Cell Line Serology Encephalitis Virus Venezuelan Equine Virology Genetic variation medicine Animals Humans RNA Messenger Epizootic Panama Strain (biology) Nucleotide Mapping Genetic Variation RNA medicine.disease Infectious Diseases Venezuelan equine encephalitis virus RNA Viral Enzootic Parasitology |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.1988.38.195 |
| Popis: | To determine the degree of genetic variation within one serologic group of Venezuelan equine encephalitis virus and the relatedness of viruses with different epidemiologic backgrounds isolated within the same country, virion RNA from 16 isolates belonging to subtype I were compared by RNase T1 oligonucleotide fingerprinting. RNA fingerprints of 12 enzootic isolates showed a large degree of heterogeneity, even though they were serologically indistinguishable. A reference enzootic strain from Colombia showed more genetic relatedness to three epizootic strains isolated in the same country, than to its own serogroup prototype strain isolated in Panama. Thus, genetic relatedness within Venezuelan equine encephalitis strains in Colombia seems to be a function of geography rather than epidemiology. |
| Databáze: | OpenAIRE |
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