Major impact of body position on arterial stiffness indices derived from radial applanation tonometry in pregnant and nonpregnant women
| Autor: | Corina Rotaru, Lucas Liaudet, Bernard Waeber, Abigael Heim, François Feihl, Letitia Jaccoud, Patrick Hohlfeld |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Supine position Physiology Manometry Posture Sitting Pregnancy Internal medicine Heart rate Internal Medicine Medicine Humans Aortic Pulse Pressure business.industry Case-control study Arteries medicine.disease Anesthesia Case-Control Studies Arterial stiffness Aortic pressure Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of hypertension. 30(6) |
| ISSN: | 1473-5598 |
| Popis: | OBJECTIVE: To evaluate the impact of body position on the arterial stiffness indices provided by radial applanation tonometry in pregnant and nonpregnant women. METHODS: Twenty-four young women (18-30 years) in the third trimester of a normal pregnancy and 20 healthy nonpregnant women of the same age were enrolled. In each, applanation tonometry was carried out in the sitting and supine position. The following stiffness indices were analyzed: systolic augmentation index (sAix), sAix adjusted for heart rate (sAix@75) and diastolic augmentation index (dAix), all expressed in % of central aortic pulse pressure. RESULTS: The sAix was apparently not influenced by body position, but the transition from seated to supine was associated with a substantial decrease in heart rate. When correcting for this confounder by calculating the sAix@75, systolic augmentation was substantially lower when individuals were supine (mean ± SD: nonpregnant 3.0 ± 14.4%, pregnant 8.8 ± 9.7%) than when they were sitting (nonpregnant 5.7 ± 13.0%, pregnant 11.1 ± 83%, P = 0.005 supine vs. seated in both study groups, P > 0.2 for pregnant vs. nonpregnant). The influence of body position on the dAix went in the opposite direction (supine: nonpregnant 9.7 ± 6.6%, pregnant 4.4 ± 3.5%; seated: nonpregnant 7.7 ± 5.8%, pregnant 3.3 ± 2.4%, P |
| Databáze: | OpenAIRE |
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