The Bnai Zion Planar Method: a simplified technique for the quantitation of the absolute renal uptake of 99mTc-DMSA in children
| Autor: | Ronen Kosakov, Lea Radan, Miguel Gorenberg, Israel Amirav |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Adolescent Urinary system Kidney Linear regression medicine Humans Radiology Nuclear Medicine and imaging Child Tomography Emission-Computed Single-Photon medicine.diagnostic_test Chemistry business.industry Infant Newborn Infant Reproducibility of Results Kidney metabolism Biological Transport General Medicine Dimercaptosuccinic acid Child Preschool Technetium Tc 99m Dimercaptosuccinic Acid Regression Analysis Female Tomography Nuclear medicine business Correction for attenuation Emission computed tomography medicine.drug |
| Zdroj: | Nuclear Medicine Communications. 31:682-685 |
| ISSN: | 0143-3636 |
| DOI: | 10.1097/mnm.0b013e3283396073 |
| Popis: | AIM AND PURPOSE: Radionuclide imaging of the kidneys using dimercaptosuccinic acid chelate labeled with technetium-99m (Tc-DMSA) is a well-established method for evaluating the extent of kidney parenchymal involvement in the scenario of urinary tract infection and for the estimation of the functional renal mass. We have developed a simplified technique, Bnai Zion Planar Method (BZPM), to estimate absolute DMSA uptake by the kidneys, which uses a shorter time of acquisition and does not require cumbersome calculations of attenuation correction. The aim of this study was to validate this technique by comparing it with the Quantitative DMSA single-photon emission computed tomography (SPECT) (QDMSA) measurements as the reference method. METHODS: Sixty-one consecutive children (mean age 5.4+/-4.8 years) were included in the study. Absolute uptake of the radiopharmaceutical by the kidneys was measured using the QDMSA SPECT methods described earlier with data acquisition of 20 min. Kidney volumes and radioactivity concentration measurements were calculated on the reconstruction data using the threshold method. For the simplified technique (BZPM), a planar posterior view of the kidneys was acquired for 1 min at the end of the QDMSA SPECT study. RESULTS: In both kidneys we observed a significant strong correlation between the two methods. BZPM measurements were very similar to those obtained using the validated QDMSA method, as determined by linear regression analysis (Pearson's r=0.924, P |
| Databáze: | OpenAIRE |
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