Epidemiology of methicillin resistant Staphylococcus pseudintermedius in guide dogs in Finland
| Autor: | Thomas Grönthal, Marjut Eklund, Matti Ollilainen, Leena Saijonmaa-Koulumies, Heli Piiparinen, Merja Rantala, Riitta Liimatainen, Veera Gindonis, Jouni Junnila |
|---|---|
| Přispěvatelé: | Departments of Faculty of Veterinary Medicine, Equine and Small Animal Medicine |
| Rok vydání: | 2015 |
| Předmět: |
Male
Veterinary medicine Meticillin Epidemiology Staphylococcus Population DIVERSITY Prevalence HEALTHY DOGS MRSA Drug resistance 413 Veterinary science medicine.disease_cause Staphylococcal infections INTERMEDIUS COLONIZATION Methicillin Dogs Risk Factors INFECTION CATS medicine AUREUS Animals Dog Diseases Risk factor education Finland education.field_of_study General Veterinary business.industry Research SCCmec General Medicine Staphylococcal Infections medicine.disease 3. Good health Cross-Sectional Studies CARRIAGE Case-Control Studies Female Methicillin Resistance business MRSP medicine.drug |
| Zdroj: | Acta Veterinaria Scandinavica |
| ISSN: | 1751-0147 |
| Popis: | Background Methicillin resistant Staphylococcus pseudintermedius (MRSP) and Staphylococcus aureus (MRSA) are common multi-drug resistant (MDR) bacteria in dogs. In 2012–2013 three dogs of the Guide Dog School of the Finnish Federation of the Visually Impaired were found to be MRSP positive. Guide dogs have regular contact with each other during their first year of life and prolonged contact when in training. Since dogs are placed in different parts of Finland after training, there is a risk for national spread of MDR bacteria. In this study the prevalence of MRSP and MRSA, as well as the risk factors for MRSP were determined in the Finnish guide dog population. MRSP isolates were investigated using molecular methods and compared to the earlier isolates. Results Out of 132 tested dogs 4 were MRSP positive thus giving the prevalence estimate of 3% (95% CI: 1–8%) for MRSP in the target population. MRSA was not detected (prevalence estimate 0%, 95% CI: 0–3%). Risk factors associated with MRSP were being a breeding bitch (OR = 8.4; 95% CI: 1.1–64.1, P = 0.012), the number of veterinary visits (OR = 1.23; 95% CI: 1.0–1.5, P = 0.025) and number of antimicrobial courses (OR = 1.63; 95% CI: 1.0–2.55; P = 0.035). Identified MRSP isolates belonged to five different sequence types (ST45, 71, 402, 403 and 404). All ST71 isolates carried SCCmec II-III, while the SCCmec type of the ST45 and ST402 (a single locus variant of ST45) isolates were non-typeable with the method used. Conclusions MRSP and MRSA had low prevalence in the studied dog population despite the close contact between dogs, and the MRSP population was heterogenic. Antimicrobial therapy and veterinary visits are risk factors for MRSP even among a small case group. Electronic supplementary material The online version of this article (doi:10.1186/s13028-015-0129-8) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink