Early Peritonitis is an Independent Risk Factor for Mortality in Elderly Peritoneal Dialysis Patients

Autor: Linsen Jiang, Zhoubing Zhan, Sheng Feng, Shan Jiang, Kai Song, Lei Yang, Huaying Shen, Zhi Wang
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Male
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system
Databases
Factual
medicine.medical_treatment
Elderly peritoneal dialysis patients
Patient characteristics
Renal function
Peritonitis
Early peritonitis
lcsh:RC870-923
Gastroenterology
Peritoneal dialysis
Risk Factors
Cause of Death
Diabetes mellitus
Internal medicine
medicine
lcsh:Dermatology
Humans
Treatment Failure
Risk factor
Mortality
Aged
Retrospective Studies
Aged
80 and over
business.industry
Proportional hazards model
Mortality rate
General Medicine
lcsh:RL1-803
medicine.disease
lcsh:Diseases of the genitourinary system. Urology
Survival Analysis
Surgery
Survival Rate
Nephrology
lcsh:RC666-701
Disease Progression
Kidney Failure
Chronic
Female
Cardiology and Cardiovascular Medicine
business
Peritoneal Dialysis
Zdroj: Kidney & Blood Pressure Research, Vol 40, Iss 3, Pp 298-305 (2015)
ISSN: 1423-0143
1420-4096
Popis: Background/Aims: The impact of early peritonitis on the outcome of elderly peritoneal dialysis (PD) patients has not been studied. We aimed to research the influence of early peritonitis on patient outcomes in elderly PD patients. Methods: This study involved elderly PD patients (age ≥65) who underwent PD between Jan 1, 2004 and Jul 31, 2013. Patient characteristics were collected in our database. Early peritonitis was defined as peritonitis within 6 months after the initiation of PD. Patient survival and technique were compared among the non-peritonitis, early peritonitis and late peritonitis groups using Cox regression analysis. Results: There were 155 subjects involved in this study. The patients were divided among a non-peritonitis group (n=78), early peritonitis group (n=32) and late peritonitis group (n=45). The organisms causing first peritonitis in the two groups did not differ significantly. After adjustment for age, diabetes, serum albumin and residual renal function, multivariable Cox regression model revealed that compared with the early peritonitis group, both the non-peritonitis group (HR 0.57, RI 0.32-0.99, p=0.046) and the late peritonitis group (HR 0.37, RI 0.16-0.75, p=0.004) exhibited a lower patient mortality rate. Conclusions: Early peritonitis is an independent risk factor for mortality in elderly peritoneal dialysis patients.
Databáze: OpenAIRE
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