Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H
| Autor: | S. P. Goff, S.H. Hughes, S. F. J. Le Grice, Z. Hostomsky |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1994 |
| Předmět: |
Ribonuclease III
biology RNase P Escherichia coli Proteins Immunology Ribonuclease H TRNA processing RNA-Directed DNA Polymerase Microbiology Virology Molecular biology Reverse transcriptase RNase MRP Retroviridae Ribonucleases Insect Science Endoribonucleases biology.protein RNase D Ribonuclease RNase H Research Article |
| Popis: | In the presence of Mn2+, reverse transcriptase of both human immunodeficiency virus and murine leukemia virus hydrolyzes duplex RNA. However, designating this novel activity RNase D conflicts with Escherichia coli RNase D, which participates in tRNA processing. On the basis of its location in the RNase H domain, we propose that this novel retroviral activity be redesignated RNase H*. |
| Databáze: | OpenAIRE |
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