Vinblastine-Induced Erythrocytotoxicity
| Autor: | Ronald D. Barr, Carol A. Rand, Alan J. Neville |
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| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Scandinavian Journal of Haematology. 28:32-38 |
| ISSN: | 0036-553X |
| DOI: | 10.1111/j.1600-0609.1982.tb02117.x |
| Popis: | At a therapeutic concentration (10−6 mol/l), vinblastine causes no significant changes of erythrocyte morphology in whole blood in vitro, but, with 30% red cell suspensions in buffer, the drug is stomatocytogenic. Several pathogenetic mechanisms are considered and the clinical relevance of this finding is assessed. |
| Databáze: | OpenAIRE |
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