Understanding the transformations of nanoplastic onto phospholipid bilayers: Mechanism, microscopic interaction and cytotoxicity assessment

Autor:	Shideng, Yuan, Heng, Zhang, Shiling, Yuan
Rok vydání:	2023
Předmět:	Environmental Engineering Lipid Bilayers Static Electricity Humans Polystyrenes Environmental Chemistry Molecular Dynamics Simulation Polyvinyl Chloride Polypropylenes Pollution Waste Management and Disposal Phospholipids
Zdroj:	Science of The Total Environment. 859:160388
ISSN:	0048-9697
DOI:	10.1016/j.scitotenv.2022.160388
Popis:	The ubiquitous nanoplastics are now considered emergent pollutants in environments. Bioaccumulation of nanoplastics is an important indicator of their hazard. In this work, molecular dynamics were used to study the uptake of five nanoplastics (polyvinyl chloride (PVC), polystyrene (PS), polylactic acid (PLA), polypropylene (PP), and polyethylene terephthalate (PET)) onto DPPC (dipalmitoylphosphatidylcholine) bilayers. Results suggest that nanoplastics became compact after they were deposited in the human body. For PET, PLA, and PS nanoplastics, a free energy barrier of 4-22 kcal mol
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc92cd07d38fe9ad7b9b5dde315d13a1 https://doi.org/10.1016/j.scitotenv.2022.160388 Zobrazit plný text záznamu Full Text from ScienceDirect