Reproducibility in circadian rhythm of ventricular premature complexes
| Autor: | U. Manzoli, A. G. Rebuzzi, Gaetano Antonio Lanza, Maria Cristina Cortellessa, Alessandra Costalunga, Enrico Scabbia, Sergio Tamburi, Michele Lucente |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac Complexes Premature Group B Coronary artery disease Basal (phylogenetics) Rhythm Heart Rate Internal medicine medicine Humans Circadian rhythm Morning Aged medicine.diagnostic_test business.industry Middle Aged medicine.disease Circadian Rhythm Anesthesia Ambulatory Cardiology Electrocardiography Ambulatory Female Cardiology and Cardiovascular Medicine business Electrocardiography |
| Zdroj: | The American journal of cardiology. 66(15) |
| ISSN: | 0002-9149 |
| Popis: | To evaluate the existence and reproducibility of a circadian rhythm of ventricular premature complexes (VPCs), 38 patients (mean age 57 +/- 17 years) with greater than or equal to VPCs/hour were studied with 24-hour electrocardiogram Holter monitoring. Nineteen patients had coronary artery disease and 19 had structurally normal hearts. A second Holter electrocardiogram was recorded in all patients from 2 to 47 days (mean 11) after the first. Chronobiologic analysis was made by single and mean cosinor methods. A significant and similar circadian rhythm of VPCs was found in the total sample both on the first (mesor 399, acrophase at 15:08, p less than 0.01) and the second day (mesor 306, acrophase at 14:47, p less than 0.05), with 2 main peaks, the first in the late morning and the second in the afternoon. However, only 18 patients (47%, group A) had a significant individual circadian rhythm of VPCs on both days, whereas 20 (53%, group B) did not have a significant rhythm in greater than or equal to 1 day. A high reproducibility of the circadian rhythm of VPCs was found in group A patients, with a difference of 2.1 +/- 1.8 hours between the acrophases of the 2 days, whereas the difference was 4.4 +/- 3.3 hours in group B patients (p less than 0.01). Among group A patients, 14 (78%) had a VPC rhythm with acrophase occurring during waking hours, whereas the acrophase of 4 (22%) occurred during the night. The reproducibility of the circadian rhythm of VPCs was not influenced by gender, presence of coronary disease, medical therapy, basal VPC number, or day-to-day variability of VPCs, although group A patients were older than group B patients (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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