Pineocytoma with diffuse dissemination to the leptomeninges
| Autor: | Caitlin Gomez, Harry V. Vinters, Antonio A. F. DeSalles, Michael T. Selch, Jeffrey Wu, Whitney B. Pope |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty endocrine system Histology medicine.medical_treatment Urinary incontinence Case Report lcsh:RC254-282 craniospinal radiation leptomeningeal dissemination Biopsy medicine pineocytoma medicine.diagnostic_test business.industry Leptomeninges Pineocytoma Magnetic resonance imaging medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Radiation therapy Oncology stereotactic radiotherapy Headaches medicine.symptom business Craniospinal |
| Zdroj: | Rare Tumors, Vol 3, Iss 4, Pp e53-e53 (2011) Rare Tumors |
| ISSN: | 2036-3613 |
| Popis: | Pineal parenchymal tumors are rare. Of the three types of pineal parenchymal tumors, pineocytomas are the least aggressive and are not known to diffusely disseminate. In this paper, we report the successful treatment of a case of pineocytoma with diffuse leptomeningeal relapse following initial stereotactic radiotherapy. A 39-year-old female presented with headaches, balance impairment, urinary incontinence, and blunted affect. A pineal mass was discovered on magnetic resonance imaging (MRI). A diagnosis of pineocytoma was established with an endoscopic pineal gland biopsy, and the patient received stereotactic radiotherapy. Ten years later, she developed diffuse leptomeningeal dissemination. The patient was then successfully treated with craniospinal radiation therapy. Leptomeningeal spread may develop as late as 10 years after initial presentation of pineocytoma. Our case demonstrates the importance of long-term follow-up of patients with pineal parenchymal tumors following radiation therapy, and the efficacy of craniospinal radiation in the treatment of leptomeningeal dissemination. |
| Databáze: | OpenAIRE |
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