Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care
| Autor: | Misha D. P. Luyer, Guusje Vugts, Renu R. Bahadoer, Marc J. van Det, Willem J. Koemans, Meindert N. Sosef, B. Görgec, Fatih Polat, Rene Scheer, Baukje Brattinga, Philip P. van der Linden, Cettela A. M. Slootmans, Richard van Hillegersberg, Marianne C Kalff, Erwin van der Harst, Marinus J. Wiezer, Frederik Lecot, Camiel Rosman, Jean-Pierre E. N. Pierie, Jan Willem Haveman, Pim B. Olthof, Peter C. Baas, Suzanne S. Gisbertz, Wendy Kelder, Víola B. Weeda, Annette D. van Dalsen, E. G. J. M. Robert Pierik, Marcia P. Gaspersz, Joos Heisterkamp, Eric J. T. Belt, Sjoerd M. Lagarde, Daan M. Voeten, Jelle P. Ruurda, Fanny J. Stoop, Peter van Duijvendijk, Linda Claassen, Victor D. Plat, Mark I. van Berge Henegouwen, Grard A. P. Nieuwenhuijzen, Jan Willem T. Dekker, Admira Ćosović, David Crull, Hein B. A. C. Stockmann, Richard P. R. Groenendijk, Guy H. E. J. Vijgen, Odin V. Sosef, Wietse J. Eshuis, Manon Drost, Martijn G. H. van Oijen, Ewout A. Kouwenhoven, Freek Daams, Wobbe O. de Steur, Johanna W. van Sandick, Henk H. Hartgrink, Donald L. van der Peet, Stijn van Esser, B. Feike Kingma |
|---|---|
| Přispěvatelé: | Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
medicine.medical_specialty
complications business.industry General surgery neo-adjuvant treatment Cancer medicine.disease Gastroesophageal Junction survival Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] All institutes and research themes of the Radboud University Medical Center SDG 3 - Good Health and Well-being medicine esophagectomy Surgery esophageal cancer business minimally invasive surgery |
| Zdroj: | Annals of Surgery, 277, 4, pp. 619-628 Annals of Surgery, 277(4), 619-628. Lippincott Williams & Wilkins Annals of Surgery, 277(4), 619-628. LIPPINCOTT WILLIAMS & WILKINS Annals of Surgery, 277, 619-628 |
| ISSN: | 0003-4932 |
| DOI: | 10.1097/SLA.0000000000005292 |
| Popis: | Objective: This study evaluated the nationwide trends in care and accompanied postoperative outcomes for patients with distal esophageal and gastro-esophageal junction cancer.Summary of Background Data: The introduction of transthoracic esophagectomy, minimally invasive surgery, and neo-adjuvant chemo(radio)therapy changed care for patients with esophageal cancer.Methods: Patients after elective transthoracic and transhiatal esophagectomy for distal esophageal or gastroesophageal junction carcinoma in the Netherlands between 2007-2016 were included. The primary aim was to evaluate trends in both care and postoperative outcomes for the included patients. Additionally, postoperative outcomes after transthoracic and tran-shiatal esophagectomy were compared, stratified by time periods.Results: Among 4712 patients included, 74% had distal esophageal tumors and 87% had adenocarcinomas. Between 2007 and 2016, the proportion of transthoracic esophagectomy increased from 41% to 81%, and neo-adjuvant treatment and minimally invasive esophagectomy increased from 31% to 96%, and from 7% to 80%, respectively. Over this 10-year period, postoperative outcomes improved: postoperative morbidity decreased from 66.6% to 61.8% (P = 0.001), R0 resection rate increased from 90.0% to 96.5% (P Conclusion: In this nationwide cohort, a transition towards more neo-adju-vant treatment, transthoracic esophagectomy and minimally invasive surgery was observed over a 10-year period, accompanied by decreased postoperative morbidity, improved surgical radicality and lymph node harvest, and improved survival. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|