Disease burden concerning hepatitis E-infected inpatients in Jiangsu province, China
| Autor: | Hui Jin, Zhaohu Yuan, Yunke Qian, Changjun Bao, Hongmin Sun, Tingting Cui, Zhong Zhang, Shilin Xu, Chunxiao Duan, Donglei Wang, Mengyun Zheng, Xuefeng Zhang, Hui Hang, Na Yue, Liling Chen, Renjie Jiang, Xiaoge Yu, Qiang Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Multivariate analysis Adolescent medicine.disease_cause Young Adult 03 medical and health sciences 0302 clinical medicine Cost of Illness Hepatitis E virus 030225 pediatrics Environmental health medicine Per capita Humans Prospective Studies 030212 general & internal medicine China Disease burden Inpatients General Veterinary General Immunology and Microbiology business.industry Public Health Environmental and Occupational Health Middle Aged Hepatitis B medicine.disease Hepatitis E Past history Hospitalization Infectious Diseases Quality of Life Molecular Medicine Female business Follow-Up Studies |
| Zdroj: | Vaccine. 38:673-679 |
| ISSN: | 0264-410X |
| Popis: | OBJECTIVE This study aimed to determine the disease burden of hepatitis E virus (HEV)-infected inpatients in Jiangsu province, China. METHODS Between July 1, 2016 and October 31, 2018, 1152 HEV-infected inpatients were identified from four cities in Jiangsu province, namely, Nanjing, Suzhou, Yancheng, and Zhenjiang. The disease burden comprised the economic burden and loss of health due to HEV infection. Factors influencing the disease burden were analyzed using univariate and multivariate analyses. RESULTS The average direct, indirect, and total economic burden for 1152 HEV-infected inpatients was US$ 4,986.40, US$ 1,507.28, and US$ 6,493.68, respectively, accounting for 46.66%, 14.11%, and 60.77% of per capita disposable income (PCDI) in Jiangsu province, respectively. The disease burden for HEV-infected inpatients with hepatitis B was significantly higher than that for other inpatients. The average EQ-5D utility value of 1152 HEV-infected inpatients was 0.72 ± 0.18 quality-adjusted life years (QALYs) and the average EQ-visual analogue score (EQ-VAS) was 0.66 ± 0.17 points. Multivariate analysis showed that the direct economic burden and the total economic burden were influenced by variables such as hospitalization days, outcomes, past history of other diseases, and regions (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect