Analysis of the imputed female urinary incontinence data for the evaluation of expert system parameters
Autor: | Pauliina Aukee, Jorma Penttinen, Jorma Laurikkala, Martti Juhola, Seppo Lammi |
---|---|
Rok vydání: | 2001 |
Předmět: |
Adult
Multivariate analysis Expert Systems Health Informatics Urinary incontinence Logistic regression Diagnosis Differential Bias Statistics Odds Ratio medicine Cluster Analysis Humans Imputation (statistics) Medical diagnosis Aged Retrospective Studies Mathematics Aged 80 and over Discriminant Analysis Numerical Analysis Computer-Assisted Signal Processing Computer-Assisted Middle Aged Linear discriminant analysis Missing data Regression Computer Science Applications Urodynamics Logistic Models Urinary Incontinence Multivariate Analysis Female medicine.symptom |
Zdroj: | Computers in Biology and Medicine. 31:239-257 |
ISSN: | 0010-4825 |
DOI: | 10.1016/s0010-4825(01)00003-8 |
Popis: | We evaluated parameters for an expert system which will be designed to aid the differential diagnosis of female urinary incontinence by using knowledge discovered from data. To allow the statistical analysis, we applied means, regression and Expectation-Maximization (EM) imputation methods to fill in missing values. In addition, complete-case analysis was performed. Logistic regression results from the imputed data were reasonable. The significant parameters were mostly those that are important in the diagnostic work-up. Moreover, directions of relations between the parameters and the stress, mixed and sensory urge diagnoses were as expected. Analysis with the complete reduced data set gave clearly insufficient results. Imputed values had a moderate agreement, but odds ratios and classification accuracies of logistic regression equations were similar. Results suggest that with these data, simpler methods may be used to allow multivariate analysis and knowledge discovery, when better methods, such as EM imputation, are unavailable. Cluster analysis detected clusters corresponding to the small normal class, but was unable to clearly separate the larger incontinence classes. |
Databáze: | OpenAIRE |
Externí odkaz: |