A single mitochondrial DNA deletion accurately detects significant prostate cancer in men in the PSA 'grey zone'

Autor: Vincent Gnanapragasm, Andrew Harbottle, Jennifer Creed, Anne George, Andrea Maggrah, Laurence Klotz, Brian Reguly
Přispěvatelé: Apollo - University of Cambridge Repository
Rok vydání: 2018
Předmět:
Male
medicine.medical_treatment
Biopsy
030232 urology & nephrology
urologic and male genital diseases
Diagnostic accuracy
Prostate cancer
Plasma
0302 clinical medicine
Prostate
Medicine
Prospective cohort study
Sequence Deletion
DNA deletion
education.field_of_study
Multi-parametric magnetic resonance imaging
medicine.diagnostic_test
Prostatectomy
Middle Aged
Mitochondrial DNA
Prostate-specific antigen
medicine.anatomical_structure
030220 oncology & carcinogenesis
Original Article
Kallikreins
Image-Guided Biopsy
medicine.medical_specialty
Urology
Population
DNA
Mitochondrial
Sensitivity and Specificity
03 medical and health sciences
RNA
Ribosomal
18S
Humans
education
Aged
Base Sequence
business.industry
Cancer
Prostatic Neoplasms
Biomarker
Prostate-Specific Antigen
medicine.disease
ROC Curve
business
Real-time PCR
Zdroj: World Journal of Urology
DOI: 10.17863/cam.21388
Popis: Purpose To determine the clinical performance of a blood-based test for clinically significant (CS) prostate cancer (PCa) (grade group ≥ 2) intended for use in men with prostate serum antigen levels in the ‘grey zone’ (PSA
Databáze: OpenAIRE
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