The potential role of auditory prediction error in decompensated tinnitus: An auditory mismatch negativity study
| Autor: | Mohammad Farhadi, Mehrnaz Mohebbi, Abdoreza Asadpour, Ahmad Daneshi, Samer Mohsen, Saeid Mahmoudian |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty media_common.quotation_subject Mismatch negativity Audiology Electroencephalography sensory memory 050105 experimental psychology 03 medical and health sciences Behavioral Neuroscience Tinnitus 0302 clinical medicine Memory Perception otorhinolaryngologic diseases Medicine Humans 0501 psychology and cognitive sciences Habituation change detection Oddball paradigm media_common Original Research prediction error medicine.diagnostic_test business.industry Sensory memory 05 social sciences Brain habituation medicine.anatomical_structure Acoustic Stimulation Scalp mismatch negativity Auditory Perception Evoked Potentials Auditory Audiometry Pure-Tone Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Brain and Behavior |
| ISSN: | 2162-3279 |
| Popis: | Introduction Some tinnitus subjects habituate to their tinnitus but some others do not and complain of its annoyance tremendously. Normal sensory memory and change detection processes are needed for detecting the tinnitus signal as a prediction error and habituation to tinnitus. The purpose of this study was to compare auditory mismatch negativity as the index of sensory memory and change detection among the studied groups to search for the factors involving in the perception of tinnitus and preventing habituation in decompensated tinnitus subjects. Methods Electroencephalography was recorded from scalp electrodes in compensated tinnitus, decompensated tinnitus, and no tinnitus control subjects. Mismatch negativity was obtained using the oddball paradigm with frequency, duration, and silent gap deviants. Amplitude, latency, and area under the curve of mismatch negativities were compared among the three studied groups. Results The results showed lower mismatch negativity amplitude and area under the curve for the higher frequency deviant and for the silent gap deviant in decompensated tinnitus group compared to normal control and compensated tinnitus group. Conclusions This study revealed a deficit in sensory memory and change detection processing in decompensated tinnitus subjects. This causes persistent prediction errors; tinnitus signal is consistently detected as a new signal and activates the brain salience network and consequently prevents habituation to tinnitus. Mismatch negativity is proposed as an index for monitoring tinnitus rehabilitation. |
| Databáze: | OpenAIRE |
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