Cervical Spinal Chordoma with Chondromatous Component in a Dog
| Autor: | B. Vidoni, A. Url, Sibylle Kneissl, A. Gruber |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Pathology medicine.medical_specialty Prednisolone Dura mater Tetraparesis Vimentin Cytokeratin Dogs Fatal Outcome medicine Animals Dog Diseases Spinal Cord Neoplasms Spinal Chordoma Physical Therapy Modalities General Veterinary biology business.industry Cartilage Anatomy medicine.disease Spinal cord Immunohistochemistry Anti-Bacterial Agents medicine.anatomical_structure Cervical Vertebrae biology.protein Chordoma business Chondroma |
| Zdroj: | Veterinary Pathology. 45:650-653 |
| ISSN: | 1544-2217 0300-9858 |
| DOI: | 10.1354/vp.45-5-650 |
| Popis: | A 7-year-old male Belgian Shepherd dog was presented with sudden onset of lateral recumbency and tetraparesis. At the level of the third cervical vertebra, magnetic resonance imaging demonstrated an intrameningeal and intramedullary mass lesion. The animal was subsequently euthanatized. A necropsy revealed a semitranslucent solid mass infiltrating dorsal and ventral dura mater and the spinal cord. Histologic examination revealed a lobulated pleomorphic mass, mainly resembling undifferentiated cartilage interspersed by spindle-shaped and polygonal cells with highly vacuolated cytoplasm (physaliphorous cells). Immunohistochemistry of the tumor cells demonstrated dual expression of vimentin and cytokeratin. Based on the histologic and immunohistochemical results, the diagnosis of a chordoma with chondromatous component was made. |
| Databáze: | OpenAIRE |
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