The impact of exercise and vitamin D supplementation on physical function in community-dwelling elderly individuals: A randomized trial
| Autor: | Naoto Endo, Kana Aoki, Mayumi Sakuma |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Vitamin
Male medicine.medical_specialty Osteoporosis Risk Assessment law.invention Cohort Studies 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Randomized controlled trial Quality of life Japan law Reference Values medicine Vitamin D and neurology Humans Orthopedics and Sports Medicine 030212 general & internal medicine Muscle Strength Exercise physiology Vitamin D Exercise Geriatric Assessment Aged Aged 80 and over business.industry Middle Aged medicine.disease Prognosis Clinical trial chemistry Physical Fitness Dietary Supplements Physical therapy Quality of Life Surgery Female Independent Living business 030217 neurology & neurosurgery Cohort study |
| Zdroj: | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 23(4) |
| ISSN: | 1436-2023 |
| Popis: | Background We investigated the impact of exercise and vitamin D supplementation on physical function and locomotor dysfunction in community-dwelling elderly individuals. Methods In total, 148 community-dwelling elderly individuals (aged ≥60 years) who were not taking osteoporosis medications participated in a 24-week intervention. The participants were randomly divided into an exercise group, vitamin D group, and exercise and vitamin D group. The participants and outcome-assessing staff were not blinded to group assignment. Exercise comprised three daily sets each of single-leg standing (1 min/leg/set) and squatting (5–6 repetitions/set); vitamin D supplementation was 1000 IU/day. Participants were contacted every 2 weeks to check on their condition and encourage continued participation. The primary outcome was lower limb muscle strength and mass; secondary outcomes were several physical function measurements, serum 25-hydroxyvitamin D levels, and results of a self-assessment questionnaire completed pre- and post-intervention. Results We analyzed data from 45, 42, and 43 participants in the exercise, vitamin D, and exercise and vitamin D groups, respectively, who completed the intervention. Locomotive syndrome, which involves reduced mobility due to locomotive organ impairment, was diagnosed in 99 participants (76.2%). Many physical function measurements improved in all groups. Lower limb muscle mass increased significantly in all three groups, with no significant differences between the groups in the degree of change. The average serum 25-hydroxyvitamin D of all vitamin D-supplemented participants increased from 28.1 ng/ml to 47.3 ng/ml after vitamin D supplementation. Conclusions Both exercise and vitamin D supplementation independently improved physical function and increased muscle mass in community-dwelling elderly individuals. Moreover, the combination of exercise and vitamin D supplementation might further enhance these positive effects. Clinical trial registry UMIN Clinical Trial, UMIN000028229 . |
| Databáze: | OpenAIRE |
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