Effects of non-dispensing pharmacists integrated in general practice on medication-related hospitalisations

Autor: Sloeserwij, V. M., Hazen, A. C.M., Zwart, D. L.M., Leendertse, A. J., Poldervaart, J. M., de Bont, A. A., de Gier, J. J., Bouvy, M. L., de Wit, N. J., Sub Voortplanting, dCSCA AVR, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology
Přispěvatelé: PharmacoTherapy, -Epidemiology and -Economics, Otorhinolaryngology and Head and Neck Surgery, Health Care Governance (HCG), Public Health, Sub Voortplanting, dCSCA AVR, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Quality management
IMPACT
Rate ratio
Pharmacists
030226 pharmacology & pharmacy
0302 clinical medicine
DESIGN
ADMISSIONS
Medicine
Pharmacology (medical)
030212 general & internal medicine
non-dispending pharmacist
Netherlands
Aged
80 and over
general practice
OUTCOMES
Confounding
PRIMARY-CARE
medication safety
Hospitalization
General practice
Original Article
Female
CLINICAL PHARMACISTS
INTERVENTIONS
medicine.medical_specialty
medication‐related hospitalisation
Drug-Related Side Effects and Adverse Reactions
Medication Therapy Management
DRUG BURDEN INDEX
03 medical and health sciences
primary care
Professional Role
Intervention (counseling)
Medication therapy management
MANAGEMENT
Journal Article
Humans
Aged
medication-related hospitalisation
Pharmacology
business.industry
Original Articles
SERVICES
Confidence interval
Pharmaceutical care
Family medicine
Pharmaceutical Services
non‐dispending pharmacist
business
Zdroj: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 85(11 SI), 2321-2331. Wiley
British Journal of Clinical Pharmacology, 85(10), 2321. NLM (Medline)
British Journal of Clinical Pharmacology, 85(10), 2321. Wiley-Blackwell
British Journal of Clinical Pharmacology, 85(10), 2321-2331. Wiley-Blackwell Publishing Ltd
ISSN: 0306-5251
Popis: AIMS: To evaluate the effect of non-dispensing pharmacists (NDPs) integrated in general practice on medication-related hospitalisations, drug burden index and costs in patients at high risk of medication problems (being 65 years or older and using five or more chronic medications).METHODS: This was a multicentre, non-randomised, controlled intervention study with pre-post comparison (2013 versus June 2014 to May 2015) in 25 general practices in the Netherlands, comparing NDP-led care (intervention) with two current pharmaceutical care models (usual care and usual care plus). In the intervention group, ten specially trained NDPs were employed in general practices to take integral responsibility for the pharmaceutical care. They provided a broad range of medication therapy management services both on patient level (e.g. clinical medication review) and practice level (e.g. quality improvement projects). In the control groups, pharmaceutical care was provided 'as usual' by general practitioners and community pharmacists, or 'as usual plus' when pharmacists were additionally trained in performing medication reviews.RESULTS: Overall, 822 medication-related hospitalisations were identified among 11,281 high-risk patients during the intervention period. After adjustment for clustering and potential confounders, the rate ratio of medication-related hospitalisations in the intervention group compared to usual care was 0.68 (95% CI: 0.57 to 0.82) and 1.05 (95% CI: 0.73 to 1.52) compared to usual care plus. No differences in drug burden index or costs were found.CONCLUSIONS: In general practices with an integrated NDP, the rate of medication-related hospitalisations is lower compared to usual care. No differences with usual care plus were found.
Databáze: OpenAIRE
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