Comparison survey of EVOO polyphenols and exploration of healthy aging-promoting properties of oleocanthal and oleacein
| Autor: | Theodora Nikou, Maria Halabalaki, Vasiliki Liaki, Leandros Skaltsounis, Günther K. Bonn, Panagiotis Stathopoulos, Aimilia D. Sklirou, Thomas Jakschitz, Eleni N. Tsakiri, Ioannis P. Trougakos |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Dietary supplement
Biology Toxicology Antioxidants Cyclopentane Monoterpenes Cell Line Healthy Aging Mice 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Phenols Olea Oleocanthal Animals Humans Food science Healthy aging Olive Oil Beneficial effects 030304 developmental biology Aldehydes 0303 health sciences Greece Polyphenols food and beverages 04 agricultural and veterinary sciences General Medicine 040401 food science Tyrosol chemistry Polyphenol Hydroxytyrosol Drosophila Food Science Olive oil |
| Zdroj: | Food and Chemical Toxicology. 125:403-412 |
| ISSN: | 0278-6915 |
| DOI: | 10.1016/j.fct.2019.01.016 |
| Popis: | Olive oil is widely accepted as a superioredible oil. Great attention has been given lately to olive oil polyphenols which are linked to significant health beneficial effects. Towards a survey of Greek olive oil focusing on polyphenols, representativeextra virgin olive oils(EVOOs) from the main producing areas of the country and the same harvesting period have been collected and analyzed. Significant differences and interesting correlations have been identified connecting certain polyphenols namelyhydroxytyrosol,tyrosol, oleacein and oleocanthal with specific parameters e.g. geographical origin, production procedure and cultivation practice. Selected EVOOs polyphenol extracts, with different oleacein and oleocanthal levels, as well as isolated oleacein and oleocanthal were bio-evaluated in mammalian cells and as a dietary supplement in theDrosophila in vivomodel. We found that oleocanthal and oleacein activated healthy aging-promoting cytoprotective pathways and suppressedoxidative stressin both mammalian cells and in flies. |
| Databáze: | OpenAIRE |
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