Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction
| Autor: | Aiki Kaul, M. Chandra, M. K. Misra |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Erythrocytes Adenosine Deaminase medicine.medical_treatment Myocardial Infarction Ischemia Myocardial Reperfusion Injury Lipid peroxidation chemistry.chemical_compound Adenosine deaminase Malondialdehyde Internal medicine Drug Discovery medicine Humans Myocardial infarction Aged Pharmacology biology business.industry General Medicine Thrombolysis Middle Aged medicine.disease Adenosine chemistry Cardiology biology.protein business Reperfusion injury medicine.drug |
| Zdroj: | Journal of Enzyme Inhibition and Medicinal Chemistry. 21:543-546 |
| ISSN: | 1475-6374 1475-6366 |
| DOI: | 10.1080/14756360600774520 |
| Popis: | A comparative study on the levels of erythrocyte adenosine deaminase and lipid peroxidation has been undertaken in patients with myocardial infarction before and after thrombolysis along with matched healthy individuals. Our findings show that adenosine deaminase activity is highly elevated in post-reperfused patients when compared to pre- thrombolysed and healthy persons. Malondialdehyde(MDA) levels are also significantly increased in post-thrombolysed patients. The study reveals an important role of adenosine deaminase in reperfusion injury in patients with myocardial infarction. |
| Databáze: | OpenAIRE |
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