The Immunological Genome Project: networks of gene expression in immune cells

Autor:	Joseph C. Sun, Veronika Lukacs-Kornek, Randall Friedline, Jamie Knell, Ananda W. Goldrath, Shannon J. Turley, Richard R. Hardy, Daniel H.D. Gray, J Adam Best, Kristen Leatherbee, Christophe Benoist, Jonathan A. Hill, Susan A. Shinton, Zheng Li, Michio W. Painter, Nora Mauermann, Daphne Koller, Scott Davis, Gordon Hyatt, Marlys S. Fassett, Joonsoo Kang, Catherine Laplace, Sokol Haxhinasto, Markus Feuerer, David H. Laidlaw, Tracy Heng, Amy J. Wagers, James J. Collins, Radu Jianu, Kutlu G. Elpek, Katelyn Sylvia, Lewis L. Lanier, Natasha Asinovski, Diane Mathis, Jessica Jarjoura, Yanan Zhu, Francis S. Kim, Ayla Ergun
Rok vydání:	2008
Předmět:	Genetics Cell type Genome Scope (project management) Immunology Gene Expression Genomics Genome project Biology Transcriptome Immune system Immune System Databases Genetic Gene expression Immunology and Allergy DNA microarray
Zdroj:	Nature Immunology. 9:1091-1094
ISSN:	1529-2916 1529-2908
DOI:	10.1038/ni1008-1091
Popis:	nology is an ideal field for the application of systems approaches, with its detailed descriptions of cell types (over 200 immune cell types are defined in the scope of the Immunological Genome Project (ImmGen)), wealth of reagents and easy access to cells. Thanks to the broad and robust approaches allowed by gene-expression microarrays and related techniques, the transcriptome is probably the only ‘-ome’ that can be reliably tackled in its entirety. Generating a complete perspective of gene expression in the immune system
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4d45fcb8b115b6890247125018ef94 https://doi.org/10.1038/ni1008-1091 Zobrazit plný text záznamu Plný text ve formátu PDF