High prevalence of vitamin D insufficiency in a United Kingdom urban morbidly obese population: Implications for testing and treatment
| Autor: | Simon Aylwin, Clare Grace, Royce P Vincent |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Urban Population Population Bariatric Surgery Type 2 diabetes vitamin D deficiency Body Mass Index Young Adult Postoperative Complications Prevalence medicine Vitamin D and neurology Humans education Aged Retrospective Studies education.field_of_study business.industry Middle Aged Vitamin D Deficiency medicine.disease Obesity United Kingdom Obesity Morbid Surgery Obstructive sleep apnea Female Secondary hyperparathyroidism business Body mass index |
| Zdroj: | Surgery for Obesity and Related Diseases. 10:355-360 |
| ISSN: | 1550-7289 |
| DOI: | 10.1016/j.soard.2013.07.017 |
| Popis: | Background Current recommendations suggest universal screening of vitamin D status before bariatric surgery to identify individuals at risk for postoperative deficiency. However little is known about the magnitude or severity of vitamin D insufficiency in the morbidly obese population awaiting bariatric surgery in the United Kingdom. The purpose of this prospective observational study was to assess the prevalence and determinants of vitamin D insufficiency in an urban multiethnic U.K. population awaiting bariatric surgery. Methods Consecutive patients attending a morbid obesity service were comprehensively assessed using a recognized obesity staging tool. Data collected included 25-hydroxyvitamin D [25(OH)D], parathyroid hormone (PTH), corrected calcium (Ca2+), body mass index (BMI), and the presence and severity of obesity associated co-morbidities, including type 2 diabetes (T2 DM), cardiovascular disease (CVD), depression, obstructive sleep apnea (OSA), and functional limitation. Results Of the 118 patients assessed, 79% were female, and 21% were male, with BMI of 52.6±9.4 kg/m2 (mean±standard deviation) and mean age of 44±11 years. Twenty-four percent had T2 DM, 28% CVD, 31% OSA, and 21% depression. Vitamin D insufficiency was found in 90% of the population, with a median serum 25(OH)D of 8.8 ng/mL. Secondary hyperparathyroidism was present in 43% of those with vitamin D insufficiency. Risk was not influenced by ethnicity, age, or gender. However severe functional limitation was associated with lower vitamin D status. Conclusion Regardless of ethnicity, vitamin D insufficiency appears to be typical among this clinic population; therefore, routine vitamin D supplementation is suggested for all individuals awaiting bariatric surgery rather than testing vitamin D status in an attempt to identify high-risk individuals. |
| Databáze: | OpenAIRE |
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