Autonomic nervous system and microcirculation in diabetes
| Autor: | L. Ricordi, Pietro Fratino, Emilio Mevio, Marco Rossi, Cesare Orlandi, Giorgio Finardi, Luciano Bernardi, Gabriele Fornasari |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
medicine.medical_specialty Physiology Autonomic Nervous System Microcirculation Electrocardiography Reference Values Internal medicine Diabetes mellitus medicine Humans Spectral analysis Skin business.industry General Neuroscience Laser Doppler velocimetry medicine.disease Autonomic nervous system Endocrinology Diabetes Mellitus Type 1 Regional Blood Flow Forearm skin Neurology (clinical) Abnormality business |
| Zdroj: | Journal of the autonomic nervous system. |
| ISSN: | 0165-1838 |
| Popis: | In order to evaluate the occurrence of sympathetic impairment of skin microvascular control in diabetes, we evaluated the spectral analysis of forearm skin laser-Doppler fluctuations in nine insulin-dependent diabetic subjects and in 21 controls of similar age. Low-frequency oscillations (around 0.1 Hz) were significantly lower in diabetics than in controls (2.333 +/- 0.340 (mean +/- SEM) units vs. 3.486 +/- 0.093 units, P less than 0.001), whereas no significant differences were found between the two groups regarding high-frequency respiration-related oscillations. These results suggest that the loss of rhythmicity in diabetic subjects is selectively related to low-frequency oscillations, mostly under sympathetic control, and is likely to be dependent on autonomic abnormality. |
| Databáze: | OpenAIRE |
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