Immunologic cross-reactivity of type A streptococcal exotoxin (erythrogenic toxin) and staphylococcal enterotoxins B and C1
| Autor: | Wayne L. Hynes, J J Iandolo, C R Weeks, Joseph J. Ferretti |
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| Předmět: |
Staphylococcus aureus
Streptococcus pyogenes Immunology Erythrogenic toxin Exotoxins Enterotoxin Cross Reactions Biology medicine.disease_cause Microbiology Cross-reactivity Enterotoxins Bacterial Proteins medicine Phylogeny Antiserum Antigens Bacterial Membrane Proteins Ouchterlony double immunodiffusion Antibodies Bacterial Infectious Diseases Parasitology Exotoxin Research Article |
| Zdroj: | Scopus-Elsevier |
| Popis: | Immunologic cross-reactivity between Streptococcus pyogenes type A exotoxin (erythrogenic toxin) and Staphylococcus aureus enterotoxins B and C1 was demonstrated by Ouchterlony double diffusion, Western immunoblot, and immunodot analyses. Specific antiserum to type A streptococcal exotoxin reacted more strongly with staphylococcal enterotoxin B than with enterotoxin C1. The reactivity of type A streptococcal exotoxin with antiserum to staphylococcal enterotoxin B was greater than that of antiserum to enterotoxin C1. These results suggest that a conserved domain is present in the three exotoxins, which most likely originated from a common evolutionary ancestor. |
| Databáze: | OpenAIRE |
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