Expansion Mechanisms and Functional Divergence of the Glutathione S-Transferase Family in Sorghum and Other Higher Plants
| Autor: | Yan-Song Cheng, Yun-Hua Chi, Shu-Ye Jiang, Srinivasan Ramachandran, Rengasamy Ramamoorthy, Jeevanandam Vanitha, Nadimuthu Kumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
abiotic stress
comparative genomics Biology Genes Plant Evolution Molecular biotic stress Gene Duplication functional divergence glutathione transferase Genetics Gene family Molecular Biology Gene Sorghum Abiotic stress food and beverages General Medicine Biotic stress Full Papers Plants Protein Structure Tertiary Gene expression profiling Glutathione S-transferase biology.protein Carbohydrate Metabolism Tandem exon duplication Functional divergence Signal Transduction |
| Zdroj: | DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes |
| ISSN: | 1756-1663 1340-2838 |
| Popis: | Glutathione S-transferases (GSTs) exist in various eukaryotes and function in detoxification of xenobiotics and in response to abiotic and biotic stresses. We have carried out a genome-wide survey of this gene family in 10 plant genomes. Our data show that tandem duplication has been regarded as the major expansion mechanism and both monocot and dicot plants may have practiced different expansion and evolutionary history. Non-synonymous substitutions per site (Ka) and synonymous substitutions per site (Ks) analyses showed that N- and C-terminal functional domains of GSTs (GST_N and GST_C) seem to have evolved under a strong purifying selection (Ka/Ks < 1) under different selective pressures. Differential evolutionary rates between GST_N and GST_C and high degree of expression divergence have been regarded as the major drivers for the retention of duplicated genes and the adaptability to various stresses. Expression profiling also indicated that the gene family plays a role not only in stress-related biological processes but also in the sugar-signalling pathway. Our survey provides additional annotation of the plant GST gene family and advance the understanding of plant GSTs in lineage-specific expansion and species diversification. |
| Databáze: | OpenAIRE |
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