Cocaine-associated thrombocytopenia
| Autor: | S.Eric Martin, Matthew J. Burday |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Drug
Adult Male business.industry Substance-Related Disorders medicine.medical_treatment media_common.quotation_subject Splenectomy Central nervous system Gingival Hemorrhage Gamma globulin General Medicine medicine.disease Thrombocytopenia medicine.anatomical_structure Cocaine Anesthesia medicine Humans Myocardial infarction Adverse effect business Mucosal bleeding media_common |
| Zdroj: | The American journal of medicine. 91(6) |
| ISSN: | 0002-9343 |
| Popis: | In this retrospective report, four male intravenous cocaine users are described with thrombocytopenia temporally related to the use of the drug. Mucosal bleeding and megakaryocytic hyperplasia occurred in all patients. The cocaine-thrombocytopenia relationship was especially apparent in one individual who developed thrombocytopenia on two separate occasions after intravenous cocaine use. Three patients were treated successfully with high doses of intravenous gamma globulin and steroids, while one patient required splenectomy. Along with the widespread use of cocaine in our society has come the recognition of a number of adverse effects of the drug. Thrombocytopenia may be added to a list that includes myocardial infarction and central nervous system complications. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|