Peste des Petits Ruminants virus infection at the wildlife-livestock interface in the greater serengeti ecosystem, 2015-2019
| Autor: | Richard Kock, Stephen L Koyie, Francis Gakuya, Geneviève Libeau, Isaac Lekolool, Arnaud Bataille, Samia Guendouz, Camilla T O Benfield, Julius Keyyu, Martin Mayora Neto, Maulid L. Mdaki, Gerald Misinzo, David Ndeereh, Bryony A. Jones, Mariam Makange, Ernest Eblate, Alexandre Caron, Harry Oyas, Peter Hongo, Krupali Parekh, Satya Parida, Mana Mahapatra, Josephine N Ndiwa, Emanuel S. Swai, Daniel Mdetele, Campaign Limo, Justin S Wanda, Ligge Shilinde, Obed Nyasebwa |
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| Přispěvatelé: | Royal Veterinary College [London], University of London [London], Institute for Animal Health, the Pirbright Institute, Sokoine University of Agriculture (SUA), Tanzania Wildlife Research Institute (TAWIRI), Kenya Wildlife Service, Partenaires INRAE, Food and Agriculture Organization of the United Nations [Rome, Italie] (FAO), Animal, Santé, Territoires, Risques et Ecosystèmes (UMR ASTRE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Eduardo Mondlane, Département Systèmes Biologiques (Cirad-BIOS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), Ministry of Agriculture, Livestock and Fisheries [Kenya], This research was funded by the Biotechnology and Biological Sciences Research Council (BBSRC), grant numbers BB/L013657/1 to the Pirbright Institute and BB/L013592/1 to the Royal Veterinary College, under the European Commission's Animal Health andWelfare European Research Area Network (ANIHWA), and by the BBSRC Global Challenges Research Fund (GCRF) grant number BB/P023002/1 to the Royal Veterinary College. Camilla Benfield was funded by a Soulsby Travelling Fellowship in One Health. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Veterinary medicine [SDV]Life Sciences [q-bio] L73 - Maladies des animaux Tanzania Animal Diseases Disease Outbreaks 0403 veterinary science Seroepidemiologic Studies Peste des petits ruminants eradication wild animals Public Health Surveillance Geography Medical 2. Zero hunger 04 agricultural and veterinary sciences Maladie transfrontière QR1-502 3. Good health Wildebeest Infectious Diseases transboundary animal disease Maladie des animaux surveillance Livestock epidemiology Topi Bétail sheep goats 040301 veterinary sciences Animals Wild Biology History 21st Century PPR Microbiology Article Peste-des-petits-ruminants virus Virus peste petits ruminants 03 medical and health sciences Virology biology.animal Peste-des-Petits-Ruminants Animals Seroprevalence Surveillance épidémiologique Ecosystem Transmission des maladies business.industry Outbreak L70 - Sciences et hygiène vétérinaires - Considérations générales Animal sauvage biology.organism_classification Kenya Cross-Sectional Studies 030104 developmental biology Herd business |
| Zdroj: | Viruses Viruses, Vol 13, Iss 838, p 838 (2021) Volume 13 Issue 5 Viruses, MDPI, 2021, 13 (5), ⟨10.3390/v13050838⟩ |
| ISSN: | 1999-4915 |
| Popis: | Peste des petits ruminants (PPR) is a viral disease of goats and sheep that occurs in Africa, the Middle East and Asia with a severe impact on livelihoods and livestock trade. Many wild artiodactyls are susceptible to PPR virus (PPRV) infection, and some outbreaks have threatened endangered wild populations. The role of wild species in PPRV epidemiology is unclear, which is a knowledge gap for the Global Strategy for the Control and Eradication of PPR. These studies aimed to investigate PPRV infection in wild artiodactyls in the Greater Serengeti and Amboseli ecosystems of Kenya and Tanzania. Out of 132 animals purposively sampled in 2015–2016, 19.7% were PPRV seropositive by ID Screen PPR competition enzyme-linked immunosorbent assay (cELISA IDvet, France) from the following species: African buffalo, wildebeest, topi, kongoni, Grant’s gazelle, impala, Thomson’s gazelle, warthog and gerenuk, while waterbuck and lesser kudu were seronegative. In 2018–2019, a cross-sectional survey of randomly selected African buffalo and Grant’s gazelle herds was conducted. The weighted estimate of PPRV seroprevalence was 12.0% out of 191 African buffalo and 1.1% out of 139 Grant’s gazelles. All ocular and nasal swabs and faeces were negative by PPRV real-time reverse transcription-polymerase chain reaction (RT-qPCR). Investigations of a PPR-like disease in sheep and goats confirmed PPRV circulation in the area by rapid detection test and/or RT-qPCR. These results demonstrated serological evidence of PPRV infection in wild artiodactyl species at the wildlife–livestock interface in this ecosystem where PPRV is endemic in domestic small ruminants. Exposure to PPRV could be via spillover from infected small ruminants or from transmission between wild animals, while the relatively low seroprevalence suggests that sustained transmission is unlikely. Further studies of other major wild artiodactyls in this ecosystem are required, such as impala, Thomson’s gazelle and wildebeest. |
| Databáze: | OpenAIRE |
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