Lateral frontal pole and relational processing: Activation patterns and connectivity profile

Autor: Harold Bekkering, Rogier B. Mars, Bob Bramson, Suhas Vijayakumar, Ivan Toni, A. Dilene van Campen, Karin Roelofs, Bart Hartogsveld, José P. Marques
Rok vydání: 2018
Předmět:
0301 basic medicine
Male
230 Affective Neuroscience
LOCAL MORPHOLOGY
DECISION-MAKING
Prefrontal cortex
Experimental Psychopathology and Treatment
Behavioral Neuroscience
0302 clinical medicine
COGNITIVE CONTROL
Models
AREAS
Neural Pathways
FACE-RECOGNITION ALGORITHMS
111 000 Intention & Action
ROSTROLATERAL PREFRONTAL CORTEX
Connectivity
Neural Pathways/anatomy & histology
fMRI
Visual Perception/physiology
Cognition
Magnetic Resonance Imaging
Frontal Lobe
Judgment/physiology
Neurological
Visual Perception
Psychology
Tractography
Adult
Adolescent
Models
Neurological
Posterior parietal cortex
150 000 MR Techniques in Brain Function
Association
Judgment
03 medical and health sciences
Young Adult
PARIETAL CORTEX
Humans
Relational processing
Association (psychology)
Resting state fMRI
Action
intention
and motor control
STATE FUNCTIONAL CONNECTIVITY
Frontal Lobe/anatomy & histology
Perception
Action and Control [DI-BCB_DCC_Theme 2]
Frontal pole
TRACTOGRAPHY
030104 developmental biology
INFERENCE
Neuroscience
030217 neurology & neurosurgery
Frontal Pole
Diffusion MRI
Zdroj: Behavioural Brain Research, 355, pp. 2-11
Behavioural Brain Research, 355, 2-11
Behavioural Brain Research, 355, 2-11. Elsevier Science
ISSN: 0166-4328
Popis: Contains fulltext : 195386.pdf (Publisher’s version ) (Open Access) The functional contribution of the lateral prefrontal cortex to behavior has been discussed with reference to several higher-order cognitive domains. In a separate line of research, recent studies have focused on the anatomical organization of this part of the brain. However, these different approaches are rarely combined. Here, we combine previous work using anatomical connectivity that identified a lateral subdivision of the human frontal pole and work that suggested a general role for rostrolateral prefrontal cortex in processing higher-order relations, irrespective of the type of information. We asked healthy human volunteers to judge the relationship between pairs of stimuli, a task previously suggested to engage the lateral frontal pole. Presenting both shape and face stimuli, we indeed observed overlapping activation of the lateral prefrontal cortex. Using resting state functional MRI, we confirmed that the activated region's whole-brain connectivity most strongly resembles that of the lateral frontal pole. Using diffusion MRI, we showed that the pattern of connections of this region with the main association fibers again is most similar to that of the lateral frontal pole, consistent with the observation that it is this anatomical region that is involved in relational processing. 10 p.
Databáze: OpenAIRE
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